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Trends in the incidence of oropharyngeal cancer
The recent rise in HPV-related oropharyngeal squamous cell carcinoma is well described. There has been a significant shift from tobacco-driven to virus-driven cancers at this anatomical site. This retrospective study analysed US tumour registry data over a long period (1973–2009)...
Total lower lip reconstruction: a review
Total or near total defects of the lower lip may result from trauma, cancer ablation or congenital causes. Defects usually involve the full thickness and include skin, muscle and mucosa. There are a number of techniques for the one stage...
Head and neck radiation and the brain
An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Nasal function in COVID-19 patients
This Turkish prospective study compared SNOT-22 outcomes as well as objective assessments of nasal secretion and clearance in 40 patients who tested positive on COVID-19 antigen PCR testing and 40 patients who tested negative. Sinonasal findings were assessed using a...
The hidden dementia in motor neurone disease
It is now well recognised that people with motor neurone disease (also known as amyotrophic lateral sclerosis) are at risk of developing frontotemporal dementia. It can be difficult to recognise the symptoms of cognitive decline in this group due to...Scientific advances in mapping syndromic hearing loss
From more than 22000 genes that we humans have, approximately 3000 genes are associated with human communication. There are tens of syndromes which have been identified to be accompanied by hearing loss. Disorders of almost every organ of the body...
Comprehensive Management of Skull Base Tumors – Second Edition
This is the second edition of a multi-author textbook first published over a decade ago. Most of the chapter authors are North American, as are the editors themselves. There is also a smattering of well-known contributors from the rest of...Establishing a medical device company: an ENTrepreneur’s experience
In 2004, while I was suturing the mucopericondrial flaps for a septoplasty, I thought to myself, “there must be an easier and faster way of doing this”. Even though I had no formal training in business or medical device development,...Music is noise
Marshall Chasin recaps what we know acoustically about music and noise, and discusses the potentially damaging levels of music, how temporary threshold shift (TTS) is not necessarily temporary and gives us some considerations for protective devices for musicians. Most of...
