You searched for "molecular"

280 results found

Voice therapy is an effective treatment for presbyphonia

The quality of an individual’s voice often declines with age. This deterioration occurs firstly as a result of vocal fold atrophy secondary to histologic alteration of the vocal fold mucosa as well as atrophy of the laryngeal musculature. Phonatory efficiency...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

In conversation with Professor Charles Liberman

Just before I left Cambridge to work with the Hearing Sciences group in Nottingham, I spent a very happy hour alone in the company of Professor Charles Liberman, the Director of the Eaton-Peabody Laboratories based at the Massachusetts Eye and...

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

Ossicular reconstruction

Ossicular reconstruction often yields disappointing results, even for the most experienced and skilled of otologists. John Dornhoffer and David Walker explain that the most important determinant of outcome is the patient’s middle ear environment, and offer some valuable words of...

Cartilage interposition versus PORP ossiculoplasty

In this Egyptian study, the authors looked at the hearing outcomes in patients who underwent ossiculoplasty with cartilage interposition versus those with partial ossicular replacement prosthesis (PORP). They looked at a total of 47 ears from 45 consecutive patients with...

Cochlear implants and therapeutics: a natural partnership?

Global awareness of cochlear implants as a solution for hearing loss is slowly increasing and gaining acceptance. The potential for combining cochlear implants with inner ear therapeutics is immense, with promise in several areas. This article takes us on a...

Endoscopic excision of cholesteatoma

In this article Vikranth Visvanathan describes an exciting development on the use of endoscopic technology in complex otological practice. Transcanal endoscopic ear surgery (TEES) is rapidly evolving as a recognised method of addressing middle ear and mastoid pathology. Since its...

Developmental stuttering: a speech-motor impairment with sensory aspects

In treating patients who stutter, understanding the effects of sensory input (i.e. auditory input) can help to direct therapeutic approaches. Sensory processing has been identified as a contributory factor in several diagnoses, notably autism and ADHD [1], however it has...

Charles Skinner Hallpike and the Hallpike Prize

The British Association of Audiovestibular Physicians introduced the Hallpike Prize in 2009 as an award to stimulate the pursuit of knowledge in relation to the field of audiovestibular medicine. Julian Ahmed celebrates the history of the great man the award...

The pioneer of precision: Wolfgang Steiner and the evolution of transoral laser surgery

It is rare that a single clinician entirely changes the course of the management of a particular condition. Steiner was one such clinician. Wolfgang Steiner was to transoral laser microsurgery what Grandmaster Flash was to hip-hop or James Brown was...

The future of inner ear drug delivery

The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...