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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...Auditory brainstem implant results in adults and children
Background The auditory brainstem implant (ABI) has been developed from cochlear implant (CI) technology and is indicated for people who have anatomical abnormalities of the cochlea or dysfunction of the auditory nerve. The majority of people who have received an...Innovative approaches to treating deafness
Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...ENT Training: a Singapore perspective
I recently had the opportunity to participate in a week’s observation with Associate Prof Thomas Loh, a head and neck surgeon with a special interest in nasopharyngeal carcinoma at the National University Hospital of Singapore (NUHS). What was striking from...
Early cochlear implant activation and its effects on the cochlea
In this article, Alhabib et al consider the changes to electrode impedance with early device activation (day one) compared to conventional activation (day 30). Activation at day 30 is a cautious approach, which has been popular for many years. However,...
Are ENT surgeons better placed to perform cosmetic ear, nasal and facial procedures?
Cosmetic surgery is an essential component of plastic surgery training and is required in order to CCT. However, the training opportunities in plastic surgery in UK are limited. The current operative requirements for plastic surgery trainees are 100 procedures during...Developing principles of swallow rehabilitation using novel animal modelling
Never let it be said that we don’t cover a wide range of topics. Camilla Dawson tells us about the crossover between swallowing in seals and in humans. Rehabilitation of swallow is complex, informed by anatomical and physiological systems and...
Complex Cochlear Implant Cases – Management and Troubleshooting
When working with cochlear implant (CI) recipients who are not responding as well as expected or their case incorporates new challenges for the audiologist, the common response is a quick panic, closely followed by a question: what do we do...Cochlear implantation in children with single-sided deafness: rationale and early findings
Cochlear Implantation (CI) in children with single-sided deafness (SSD) is a controversial treatment option. Profs Karen Gordon, Papsin and Cushing discuss the rationale and early findings on the relative success of achieving binaural hearing for SSD with CI. If you’d...
Location, location, location: How to get the steroid where you need it, in chronic rhinosinusitis
What almost all current guidelines on chronic rhinosinusitis have in common is the importance of intranasal steroid (INCS) use. However, it is increasingly understood that the efficacy of INCS depends on their efficient delivery to the point of need, i.e....
