You searched for "retraction"
Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
A new era in the treatment of recalcitrant nasal polyps?
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be difficult to treat effectively in patients with aggressive or recalcitrant disease. Omalizumab (Xolair) is a monoclonal anti-IgE antibody with proven benefits for patients with moderate/severe asthma and CRSwNP, but this study looks...
When to operate on a patient without chronic disease?
As ENT surgeons, we spend a lot of time managing chronic rhinosinusitis, so a review and update on the management of the acute disease is always helpful. The standard medical treatment of antibiotics, nasal steroids and nasal decongestants are reported...
Painful temporomandibular joints
This paper is a meta-analysis of randomised controlled trials comparing arthrocentesis with conservative management in painful and restricted mouth opening temporomandibular joint symptoms. Temporomandibular joint dysfunction comprises a spectrum of disorders commonly involving facial pain and loss of oral function...
Helmets make a difference in bicycle injuries
This is a meta-analysis of maxillofacial injuries arising from riding a bicycle. The incidence of maxillofacial fractures in cycling accidents varies from 3-20% and, whilst the effectiveness of helmets in preventing traumatic brain injuries is well known, their protective effect...
Tympanometry with cochlear implants
Multifrequency and multicomponent tympanometry enables evaluation of minute changes in the middle ear system as well as changes in resonant frequency. Change in resonant frequency would indicate a change in the natural characteristics of the middle ear, such as mass...
Posterior nasal neurectomy – long-term data shows tailing off of benefits but still improvement after three years
It is well understood that allergic rhinitis has a very detrimental effect on quality of life for afflicted patients. This study looks at patients with allergic rhinitis but no other associated sinonasal or respiratory diagnoses. Patients with a history of...
Outcomes and progress of a well-designed one-stop head and neck lump clinic
With increasing caseload of head and neck cancer and the fact, as reported by UK Government in October 2024, that over half of these cases are diagnosed at an advanced stage, the need for early diagnosis and prompt management is...A parent’s journey: beyond the diagnosis
Tamsin Coates lives in Wallesey, UK and talks about coming to terms with the difficulties and joys of having two deaf children. Here she explains about the early days and the impact of their diagnosis upon the family. Thinking back...
Medical control of allergic rhinitis in children
The authors of this randomised trial aim to answer an important question – which is better: daily versus on demand use of intranasal steroids (fluticasone probionate) or antihistamines (levocetirizine dihydrochloride) for symptomatic control of allergic rhinoconjunctivitis secondary to pollen? The...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
