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Cocaine detection hours after FESS
This is a very interesting article from Australia regarding the bioavailability of cocaine following atomised application prior to endoscopic sinus surgery. The well-established practice of preparing the nasal mucosa for sinus surgery involves the placement of a usually modified Moffett’s...Laryngeal papillomatosis
Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...Addressing the hearing needs of people with dementia
Dr Dawes provides a comprehensive overview of hearing needs of persons with dementia coupled with recommended guidelines for hearing-related considerations when assessing and intervening with persons with dementia. With ageing populations, we face a global dementia challenge. Rates of both...
Hearing difficulties and memory problems
Since the Lancet Commission report in 2020, we have all been aware that untreated hearing loss is potentially one of the biggest modifiable risk factors for dementia in midlife. Hearing loss is also associated with other risk factors for dementia,...In conversation with Professor Janet Wilson
As she approaches her retirement from clinical practice, Professor Janet Wilson speaks to our Editor (and fellow laryngologist) Declan Costello about surgical training, research, diversity, literature and the future. You have had an immensely successful career in ENT – how...Why screen for hearing loss in adults?
Introduction Hearing loss affects over 10 million people in the UK – one in six of the population. Of over 50-year-olds 41.7% are estimated to have some form of hearing loss. This rises to 71.1% of over 70-year-olds, over half...The curse of Sports Illustrated
“Not a supernatural curse, but a basic statistical concept of blinding simplicity.” What is ‘regression to the mean’? I am reliably informed that our former North American colonies publish a periodical known as Sports Illustrated (note, incidentally, the characteristically incorrect...
Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017
Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...
Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm
Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...
