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Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...

A psychophysical perspective on single-sided deafness and its treatment by cochlear implants

Bob Carlyon gives us a psychophysical perspective on the hearing benefits that can and cannot be achieved for patients with single-sided deafness with a cochlear implant, and discusses some of the challenges in maximising the effectiveness of the treatment. He...

Use of automated audiometry for faster patient access to audiology services?

Manual audiometry has long been the gold standard for establishing hearing thresholds. In recent years, a number of automated audiometry applications have reached the market. In this article, a team from Ireland have put a version of automated audiometry to...

SEQaBOO: SEQuencing a Baby for an Optimal Outcome

There are at least 15 countries now running genome sequencing projects. The team in Manchester, UK, and Boston, USA, share their SEQaBOO project. Abstract SEQaBOO (SEQuencing a Baby for an Optimal Outcome) will transform newborn hearing screening (NBHS) by bringing...

Genetics and the newborn hearing screen: the future is now

Eliot Shearer shares the progress being made with newborn hearing screening 60 years on from where it started, and future directions for identifying hearing loss using physiologic, genetic and cCMV screening. Newborn screening had its birth in the early 1960s,...

Active middle ear implants and bone-anchored hearing systems

The implantable hearing device market has grown significantly over recent years. But as conventional hearing aids improve and cochlear implant candidacy widens, what is the role for active middle ear implants and bone anchored hearing systems, and how should we...

Endoscopic ear surgery in children

The benefits of endoscopes in otologic surgery, which have become increasingly widely appreciated in recent years, are very well suited to the management of paediatric middle ear disease. Although one might imagine that the smaller ear canal of a child...

Auditory brainstem implant results in adults and children

Background The auditory brainstem implant (ABI) has been developed from cochlear implant (CI) technology and is indicated for people who have anatomical abnormalities of the cochlea or dysfunction of the auditory nerve. The majority of people who have received an...

A binaural detection task that reveals deficits in listeners having ‘slight’ or ‘hidden’ hearing loss

The association of degraded binaural processing in adults with clinically defined ‘slight’ or ‘hidden’ high frequency hearing loss is of great interest to clinicians if it can be measured. Leslie R Bernstein and Constantine Trahiotis share their findings in measurements...

Effects of blast and acoustic trauma: assessment of hearing status on war veterans

Introduction Acoustical conditions of the military are often dangerous and there is a real risk of blast trauma and acoustic trauma [1, 2]. Levels of military noises maybe reach up to 125 dBA [3]. Weapons produce instant shock waves (10μs)...