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Can writing reveal the timeline for future dementia diagnoses?

Frontotemporal dementia is the term for a group of dementias affecting behaviour and language. Thirty percent of FTD cases are associated with autosomal dominant mutations. There are three main genes that account for the majority of these genetic FTD cases...

NHS collaboration and partnership with the pharmaceutical and medical devices industries

Historically the relationship between industry and the NHS has been a cautious one. Both sides have typically worked with only partially disclosed agendas, under a pervading fear of finding themselves on the wrong end of a win-lose negotiation. Things have...

Bringing space science to balance and tinnitus

Jameel Muzaffar is a specialist registrar in ENT surgery in the West Midlands. His research interests include applications of imaging to ENT. Chris Coulson is a consultant otologist, particularly interested in the development of technological solutions. He is part of...

Leisure listening does not affect the hearing of young people

The existing literature highlights concerns regarding the possibility of leisure activities involving listening to music on portable music players causing hearing loss. However, there is much speculation regarding actual effect. This article outlines a project involving young persons aged between...

Aerosol research and performance

Is singing safe? This was a question asked around the world at the start of the pandemic in early 2020. Natalie Watson and Chris Orton tell us about a rapidly-convened research group that led to profound changes in UK Government...

Guidance to protect doctors and dentists during COVID-19 pandemic

ENT and facial surgeons issue guidance to protect doctors and dentists during COVID-19 pandemic. Two surgical specialty associations have come together for the first time to protect dentists and doctors examining and treating patients who may have COVID-19 (coronavirus), but...

Influence of smoking on vocal fold polyps

A vocal fold polyp is a benign lesion related to phonotrauma which induces upregulation of inflammatory processes and histological changes can occur in the epithelium and lamina propria. Whether smoking produces additional or enhanced changes is the subject of this...

Head and neck cancer deaths to cost $535 billion by 2030

More than 500,000 people across the globe will die this year from head and neck cancer, which is the sixth most common cancer in the world and comprises malignancies of the nose, mouth, throat, larynx, and neck. Assuming current trends...

What do animal models tell us about tinnitus and hyperacusis?

Do animals have tinnitus? The obvious question to ask is: do animals have tinnitus? It is known that tinnitus is a conscious percept and as such affected by attention and not audible during sleep. For it to be demonstrated that...

Tele-audiometry – a ShoeBOX solution

Access to hearing assessment is a global challenge. In relation to the global burden of hearing loss World Health Organisation’s (WHO’s) recent estimate (2013) is that 360 million people in the world have disabling hearing impairment. Two-thirds of these people...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

Development of a new negative-pressure ventilatory support device: Exovent

The pandemic has driven innovation in ways that we have not seen for many decades. Intensive care medicine and ENT have been at the forefront of these advances, and our good friends David Howard (never one to put his feet...