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CRSwNP initiation, not always an interleukin fault
CRSwNP, similar to asthma, is an inflammatory disorder (type II) with eosinophilia and raised IL-5 and IL-13. Inflammation in CRSwNP is thought to be started by IL-25, IL-33 and thymic stromal lymphopoietin (TSLP), all of which form an important part...
Paediatric idiopathic sudden sensorineural hearing loss
This Turkish retrospective study looked at the radiological and clinical characteristics, prognostic factors and treatment outcomes in children diagnosed with idiopathic sudden sensorineural hearing loss (ISSNHL). Forty-eight children were included over an eight-year period. Complete recovery (CR) was achieved in...British Academy of Audiology Position Statement
The British Academy of Audiology (BAA) has released a position statement on the future of NHS Adult Hearing Loss Management. The Board of Directors’ position is that audiology services must be free at the point of access for everyone who...
The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...From the editor Jan/Feb 2025
Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. E: d.costello@nhs.netTW / X: @Voicedoctor_uk As we slip seamlessly into the new year, I hope you have all had a good break and that...Embracing the changes prompted by lockdown
March 2020 introduced the concept of lockdown to audiology services in the NHS, prompting a rethink of how to best provide hearing care. In this issue, we hear from Hanna Jeffery, a Clinical Scientist working at the Royal Glamorgan Hospital...
Cadaveric variation of nasolacrimal duct lateral nasal wall landmarks
Twenty mid-sagittal head sections of 10 fresh frozen cadavers were studied after removal of the nasal septum. This study showed that the most anterior projection of the middle turbinate head was noted to be anterior to the nasolacrimal duct in...
Talking it through: voice therapy
The authors begin this article by highlighting two issues in voice therapy: 1. the high rate of relapse and 2. poor attendance at appointments. They attribute this to there not being carryover (or generalisation) work embedded into most voice therapy...
Lost and sound: exploring hyperbaric oxygen therapy for refractory SSNHL
Can hyperbaric oxygen therapy (HBOT) offer a breakthrough for patients with refractory sudden sensorineural hearing loss (SSNHL)? SSNHL is defined as acute hearing loss of ≥30 decibels in three consecutive frequencies within three days. Typically, it’s treated with two weeks...Jarrod Homer and Stuart Winter: Development of the sixth edition of the UK multidisciplinary head and neck cancer guidelines
Head and neck cancer care is a complex and constantly evolving field. What’s new and how are national guidelines on the subject produced? We spoke to Professors Homer and Winter, the lead authors of the most recent edition of the...Jarrod Homer and Stuart Winter: Development of the sixth edition of the UK multidisciplinary head and neck cancer guidelines
Head and neck cancer care is a complex and constantly evolving field. What’s new and how are national guidelines on the subject produced? We spoke to Professors Homer and Winter, the lead authors of the most recent edition of the...
