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IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Surgery or medicine: when should we stop trying to be conservative?

Although most otolaryngologists would agree that surgery improves the outcomes of patients with CRS when medical treatment has failed, both Cochrane reviews state that there is no proof of improved efficacy of surgery over medicine – however, that was after...

A new biomarker for chronic rhinosinusitis

This Chinese study looked at the feasibility of periostin (usually found in bone and lung tissue) as a biomarker for chronic rhinosinusitis. They sampled ethmoid mucosa in 12 patients with chronic rhinosinusitis without nasal polyposis (CRSsNP) and 25 patients with...

Saline irrigation in CRSwNP after surgery

This article, largely from Germany, aims to prove the effectiveness of nasal saline irrigation in postoperative patients with CRS with nasal polyps. A prospective, single blinded randomised trial was designed with an irrigation and non-irrigation arm. Patients who underwent sinonasal...

Olfactory neuronal damage in sinusitis

So many patients with nasal disorders have poor olfactory function, yet sometimes the nose may seem comparatively clear of conductive problems. This study postulated that neuronal damage in the olfactory apparatus would lead to a leakage of neuron specific enolase...

Contralateral OAEs in children

Several studies indicate that small changes in the medial olivocochlear (MOC) reflex may possibly be associated with certain pathologies. This could be measured by using contralateral acoustic stimulation (CAS) and observing suppression in otoacoustic emissions (OEAs). The main aim of...

CATE in people with dementia

Behavioural hearing tests may be difficult to perform for people with dementia. The aim of this study was to investigate if the cortical automatic threshold estimation (CATE) may be used as an alternative to the pure tone audiometry test. Six...

What is balloon eustachian tuboplasty (BET)?

Eustachian tube dysfunction (ETD) is the result of a combination of factors that interfere with the mucosal functional or cartilaginous structures. Failure to open the eustachian tubes can cause aural pain, pressure in the ears, muffled hearing, crackling/popping sounds in...

CT guided cochlear implant programming improves performance

There is currently no national (UK) consensus on imaging patients for cochlear implantation. This paper may change that. It has shown increased hearing and quality of life in paediatric cochlear implant (CI) users when the programming has been assisted by...

Tympanometry with cochlear implants

Multifrequency and multicomponent tympanometry enables evaluation of minute changes in the middle ear system as well as changes in resonant frequency. Change in resonant frequency would indicate a change in the natural characteristics of the middle ear, such as mass...

Nasal decongestants don’t improve Eustachian tube function

Prescribing nasal steroids and decongestants. It’s something most of us do routinely, in an effort to reduce chronic middle ear effusion in an adult by trying to improve eustachian tube (ET) patency. This study used clever devices (tube manometry and...

Otologic Surgery - 5th Edition

Otologic Surgery 5th Edition, edited by Derald Brackmann, Clough Shelton, Moises Arriaga and Richard Gurgel, is a textbook masterpiece. The book is written in tribute to the editors’ mentors: Drs Howard House, William House and James Sheehy, whose pioneering work...