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Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

Thyroid nodules – time for a rational imaging approach

“The more you know, the harder it is to take decisive action. Once you become informed, you start seeing complexities and shades of gray. You realize that nothing is as clear as it first appears. Ultimately, knowledge is paralyzing.” Calvin,...

Frontiers 2025

By Harvey Coates, Clinical Professor University of Western AustraliaThe 14th Frontiers in Otolaryngology, Head and Neck Surgery was held in Hobart, Tasmania and sponsored by the Passe and Williams Foundation (formerly known the Garnett Passe and Rodney Williams Memorial Foundation)....

Vicarious (nasal) menstruation

Hippocrates himself is known to have said that when a woman’s menses are due, but instead of the usual vaginal menstrual flow, she has a haemorrhage from the nose, then this is a sure sign of pregnancy [1]. Artist’s impression...

Michelle – Chevalier Jackson’s choking doll: Simulation in paediatric airway management 100 years ago

Simulation has become an indispensable tool in modern paediatric airway management as it offers clinicians the opportunity to practise complex procedures in a safe, controlled environment [1], although challenges will always remain in replicating the true anatomical proportions and tactile...

Therapeutic ultrasound for tumours

This review article provides details about the potential applications of transcranial focused ultrasound (FUS), its mechanism of action and the studies that have set the basis for its use in neuro-oncology. FUS is an emerging modality of therapy for various...

Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

Tinnitus in patients on therapy with PPI and in PPI non–users

Tinnitus is a chronic and debilitating condition and approximately 10% of the population is afflicted. A myriad of pharmacological treatments for tinnitus are available but only a few controlled studies have shown positive results. The relationship between proton pump inhibitors...

Chronic rhinitis endotypes

Chronic rhinitis (CR) is common with up to 30% of the population affected, with a significant impact on quality of life. CR includes several phenotypes with different pathogenesis including allergy, autoimmune, age, occupation, pregnancy, neurogenic and drugs. Such variation means...

Post-total laryngectomy constipation

This cross-sectional study investigated the prevalence of chronic constipation post total laryngectomy (TL) and after total pharyngolaryngectomy (TPL). For the study, the authors used a self-completed patient questionnaire to evaluate the prevalence and factors related to it. Patients using opioids,...

Still not smelling

Post-Covid anosmia/hyposmia is a troublesome persistent symptom for lots of patients. Management is still elusive. This was a nationwide survey of ENT practitioners. Of the 715 surveyed members, only 7.4% responded. Most performed a nasal endoscopy, 60% ordered an MRI...