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1554 results found

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Static positional nystagmus

This study aimed to clarify the interpretation of positional nystagmus (PN) by looking at the current criteria for significance of PN, comparison of PN in symptomatic patients with normative data, prevalence of PN among participants with balance problems and assessing...

Screening: evaluating the outcomes of early intervention

Newborn hearing screening is now the accepted standard of care in several countries, and is becoming increasingly more established worldwide. White [1] reported eight countries screening over 90% of newborns, ten screening between 25-89% of births and a further 54...

Tinnitus in patients on therapy with PPI and in PPI non–users

Tinnitus is a chronic and debilitating condition and approximately 10% of the population is afflicted. A myriad of pharmacological treatments for tinnitus are available but only a few controlled studies have shown positive results. The relationship between proton pump inhibitors...

Is there a cause-and-effect relationship between allergic rhinitis and chronic rhinosinusitis?

This review examines the possible causative relationship between allergic rhinitis (AR) and chronic rhinosinusitis (CRS) that has long been proposed. Many observational and experimental studies exist, however no clear and definitive connection has been established. This is mainly due to...

Swahili speech development in pre-school children

This study describes the speech development of 24 typically developing first language Swahili speaking children between the ages of three and five years 11 months in Dar es Salaam, Tanzania and was motivated by the 2013 position paper drafted by...

Hearables: in-ear sensing devices for recording of physiological signals

Colver Ken Howe Ne, Jameel Muzaffar and Manohar Bance discuss the potential of hearable systems to monitor physiological signals (e.g. from brain or heart, blood pressure, body temperature) unobtrusively. Such adaptations require high-quality sensors and sophisticated de-noising signal processing on...

How has management and outcomes of necrotising otitis externa changed over the past decade?

Necrotising otitis externa (NOE) remains a challenging condition for ENT departments, particularly with the increased prevalence of diabetes mellitus (DM) in the general population. There is no international consensus on treatment, although many institutions now have local guidelines drawn up...

Prevention is Better than Cure: Learning from Adverse Events in Healthcare

Ian Leistikow has an impressive CV; as Senior Inspector at the Dutch Healthcare Inspectorate and a member of the Strategic Advisory Board of the International Forum on Quality and Safety in Healthcare, it is clear he is passionate about advancing...

Reasons for rejection of BAHA in patients with unilateral hearing loss

Ever since Tjellström first developed the procedure of BAHA implantation, the techniques have come a long way towards faster and more convenient surgical methods to offer better hearing for a wide variety of conditions. Unilateral hearing loss has now been...

Developing principles of swallow rehabilitation using novel animal modelling

Never let it be said that we don’t cover a wide range of topics. Camilla Dawson tells us about the crossover between swallowing in seals and in humans. Rehabilitation of swallow is complex, informed by anatomical and physiological systems and...

The effects of polypharmacy in the elderly

Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...