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Malignant transformation of leukoplakia in previous cancer patients

This is a retrospective study from Taiwan assessing risk factors in developing oral squamous cell carcinoma from surgically excised oral leukoplakia in patients with a previous oral cancer, the underlying thought being that patients with an oral carcinoma have a...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Patient-related factors that require revision surgery for otosclerosis

Stapes surgery for otosclerosis has a high success and low complication rate but, over a period of time, good results can deteriorate, requiring revision surgery. In this study, the authors have focused on patients’ demographic data as predictive factors for...

Impact of Covid-19 on secretory otitis media (SOM) in terms of rate of intervention, effusion detected intraoperatively and seasonal variation

It is widely known that secretory otitis media (SOM) has seasonal variations. In well-judged cases, there is middle ear effusion found at the time of surgery. In this retrospective study, the authors have tried to assess if Covid-19 changed these...

Which patients are suitable for surgery in recurrent head and neck cancer?

Currently, radiotherapy and chemotherapy is the most common modality used in the management of primary head and neck squamous cell carcinomas (HNSCC). Unfortunately, around 50% of patients experience disease recurrence (rHNSCC). Surgery is therefore often used as a salvage treatment....

In conversation with George Tavartkiladze

For decades, Professor Tavartkiladze has been the personification of Russian audiology and its best known ambassador on the international stage. Hailing from the republic of Georgia, he has led countless seminal initiatives within Russia to advance the science and practice...

Patient-centred and accelerating progress: two organisations changing the landscape for rare skull base tumours

Patient-led organisations are transforming care for rare skull base tumours by connecting patients, clinicians and researchers to accelerate diagnosis, support and scientific progress. Askull base tumour diagnosis is a difficult time for any patient, but it is made more uncertain...

Determinants influencing ageing within the vestibular system

The observation that ageing affects vestibular function is not new. However, using a whole population survey, the authors set out to evaluate quantitatively factors responsible for the age-related changes in vestibular function. As part of a national survey on health...

Music and cochlear implants

Introduction The introduction of multichannel cochlear implants (CIs) in the early 1980s provided children and adults with severe and profound hearing losses with greatly improved speech perception skills. In this paper, however, I am going to focus on an area...

William Hunter’s work on the anatomy of the human ear

The Hunterian Society offers an annual award for an essay and presentation on a subject of relevance to John or William Hunter, or medicine in the 18th Century. This article is based on Emma Stapleton’s 2014 winning essay, which was...

In conversation with Lawrence Cleary

Lawrence Cleary is an art dealer and an ENT patient. He is also a recipient of an MBE for his contribution towards establishing the first multichannel cochlear implant programme in the UK. In this article he discusses with Katherine Conroy...

Carnoy’s and the KOT

This is a retrospective review of 105 patients with keratocystic odontogenic tumours treated over a 23-year period with a mean follow up of 86 months. The recurrence rate was 11.4%. Permanent neuro-sensory deficit of the inferior alveolar nerve 16%. Younger...