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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Robotics in rhinology – fantasy or the future?

Robotic surgery is advancing, but its use in rhinology lags due to spatial constraints and high costs. Innovations in flexible robots may bridge this gap in the future. We are in a new era, one of artificial intelligence and robotics....

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

The role of metrics in studies of hearing and cognition

Introduction When perceiving sounds in real-world listening environments, older adults encounter several sources of degradation that can interfere with the perceptual process (Figure 1). Target signals (i.e. the sounds that a listener wants to focus on) have specific acoustic characteristics...

Does pollution worsen inflammatory nasal problems?

This ambitious study, conducted over a period of four years, assessed 27,863 patients and compared levels of allergic rhinitis (AR) or chronic rhinosinusitis (CRS) with the levels of air pollution recorded, as assessed by levels of particulate matter (PM10). They...

Lessons from the outcomes of children with hearing loss study

The Outcomes of Children with Hearing Loss (OCHL) study of 300 children with hearing loss has targeted several factors that are under the control of audiologists and parents. Drs McCreery and Walker discuss how these ‘lessons learned’ can lead to...

The ear-brain connection in cochlear implant users: learning to listen again

While the cochlear implant (CI) has been a tremendous success in restoring hearing to deaf individuals, the implantation outcome still varies across CI users [1]. Some demographic factors, such as duration of deafness, and peripheral factors, such as electrode placement,...

Running a post-COVID smell clinic

Over the past year, much of our effort as a speciality has been directed towards crisis management and keeping services afloat. Our practice has changed in untold ways, but unprecedented numbers of patients with smell disorders will increasingly require our...

Righting the paralysed lip

Many surgical procedures that otolaryngologists perform put the facial nerve at risk of injury, a complication that the surgeon and patient fear alike. Unfortunately, injuries to the nerve can and do happen despite adequate precautions, and facial paralysis may be...

When should revision FESS leave you reaching for the script pad?

This very interesting work from the professorial team in London seeks to define a group of patients with CRSwNP who may benefit from early biological treatment since they are at risk of failure of surgical and conventional medical management. Approximately...

Role of intratympanic corticosteroid for treatment of Bell’s palsy and Ramsay Hunt syndrome

Acute peripheral facial palsy occurs annually in 30 in 1,000,000 individuals in the general population. Bell’s palsy and Ramsay Hunt syndrome account for about 70% of cases of peripheral facial palsy. They are believed to be caused by viral reactivation...

Facial pain: the differential diagnosis in an ENT clinic

The patient presenting with facial pain can be a heartsink. Fear not – Bhaskar Ram and Sangeeta Maini are here with a succinct overview of the common non-sinogenic causes of facial pain and headache, and how to manage them. Facial...