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2587 results found

A drug to prevent hearing loss caused by ototoxic therapeutics

This editorial briefly highlights the progress made in discovering a compound named ORC-13661, which shows the potential to alter the response of hair cells to ototoxic medication. In the late 1980s, inner hair cells that were lost secondary to noise...

Role of ultrasonography-guided fine-needle aspiration in management of the neck after chemoradiotherapy

Primary chemoradiotherapy (CRT) is a well-established treatment for locally advanced head and neck squamous cell carcinoma (HNSCC). However, not every patient has a complete response to this treatment modality, necessitating eventual salvage neck dissection. Some patients with persistent adenopathy following...

Invasive differentiated thyroid cancer

The majority of patients presenting with differentiated thyroid cancer have early small disease with excellent long-term outcomes. However, aerodigestive tract invasion is reported in around 10% of case series and is a poor prognostic factor. This article has been authored...

Swallow assessment: is clinical judgement or objective measurement more reliable?

Swallowing difficulties are life threatening and are the most common referral reason to speech and language therapists working with the adult population. Video fluoroscopic examination is a common instrumental tool used to assist in the assessment of the risk of...

Deep space neck infections and their management

This article explores the approach to managing patients with deep space neck infections. Clearly, an understanding of the fascial planes within the neck is required which then provides an understanding of the route of spread in these cases. The authors...

Carotid paragangliomas and their management

Paragangliomas in the head and neck are most frequently associated with the carotid artery, classically at its bifurcation and splaying the internal and external vessels. Despite their commonality at this site, large studies of these rare tumours are still lacking...

The initial management of nasal trauma

Fractures of the nose are the most common facial fractures and reported to be the third most common fracture of the human skeleton. Nasal trauma can lead to obvious or more subtle loss of function or form and cosmetic compromise....

Vestibular screening in occupational medicine

Occupational vestibular disorders carry a high medico legal and economic burden. The occupational medicine physician must rely on rapid, non-invasive, economical and reproducible screening tests. This article compares the simplified caloric test of Veits (CTV) with the skull vibration-induced nystagmus...

The effect on taste buds due to severing of the chorda tympani nerve

The long-term histological effect on taste buds following cutting of the chorda tympani in humans is not clear. Confocal laser scanning allows in-vivo examination of the same group of taste buds and is aiding our understanding of why patients recover...

Head and neck myxofibrosarcoma: a case report and review of the literature

Myxofibrosarcoma is the most common soft tissue sarcoma that occurs in late adult life, peaking in the seventh decade, and it is mainly encountered in the lower extremities. Cases within the head and neck region are extremely rare and to...

The unknown primary again

In this retrospective study of 35 patients, the authors followed a systematic protocol for the detection and management of malignant cervical lymph nodes without an apparent primary lesion. Although their one, three and five year survival results are consistent with...

Is bone scanning still of value?

This is an article from Australia of 109 patients, 83 of which had CT, 72 MRI and the presence of bone invasion on imaging was compared with the histopathology. Bone invasion was present in 44 of 109 resection specimens. Bone...