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Genetic discovery using animal models: presbyacusis
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...St Blaise - patron saint of the throat
In a previous article, we looked at some interesting legends surrounding patron saints of the ear and hearing [1]. As we celebrate the Feast Day of St Blaise of Sebastia on 3 February, we hear some fascinating tales and myths...Accurately diagnosing reflux to direct personalised treatment
Laryngopharyngeal reflux (LPR) frequently causes severe extra-gastrointestinal symptoms – such as a persistent cough, vocal problems, asthma or difficulty swallowing – that can be easily confused with a common cold and allergies.Paediatric vestibular evaluation
Richard E Gans is a renowned expert in the areas of vestibular evaluation and rehabilitation techniques. In the first of two articles (see here for the second article), Dr Gans gives an overview of the approach he and his team...
Can telemetry predict sleep apnoea in Pierre Robin sequence?
The aim of this study was to see if telemetry data gathered on patients with Pierre Robin sequence (PRS) correlated with sleep study data. A retrospective review of 46 patients from a tertiary referral centre were included in the study....
Diagnosis of obstructive sleep apnoea hypopneoa syndrome (OSAHS) without sleep studies
Polysomnography is considered the ‘gold standard’ in the diagnosis of sleep apnoea but it is expensive and difficult to perform in children. Diagnosis based on subjective judgement is often inaccurate. An accurate diagnostic scale based on clinical parameters could obviate...
‘Close’ surgical margin in oral tongue redefined, 2.3mm is as good as 5mm
Gold standard treatment of squamous cell carcinoma (SCC) of the oral tongue remains surgical resection of the primary tumour with negative margins. The primary goal is the complete excision of the tumour with no residual cancer cells left behind. A...
Managing the most common branchial arch anomaly
This article is a well written, helpful summary of the management of the most common branchial anomaly in children – the second. These are characterised as cysts, sinuses or tracts between the anterior border of sternocleidomastoid, coursing between the internal...
Post-thyroidectomy vocal cord palsy: are there long-term sequelae?
This is a well written paper utilising the Hospital Episode Statistics dataset for all thyroidectomies performed in England between 2004 and 2012. The study had a very impressive 43,515 participants and only included young, fit patients undergoing thyroidectomy once for...
Investigations in the management of OSA in children
The purpose of this study was to pick up variation of practice across the UK in the assessment and management of children with suspected OSA, particularly with reference to pulse oximetry and polysomnography. A questionnaire-based survey revealed that preoperative pulse...
CAD/CAM assisted mandibular reconstruction or freestyle?
The gold standard for the reconstruction of the mandible is a free bone flap and the fibula is commonly used. The fibula is a straight bone and presents considerations and difficulties in the formation of a U-shaped neo-mandible. Computer aided...
