You searched for "genes"
Breaking barriers in Uganda: the story of Elaine Mukaaya
More than 9% of sub-Saharan Africa’s one billion people live with disabling hearing loss, with children having among the highest rates of childhood hearing loss in the world [1]. Sadly, in concordance with the inverse care law – proposed by...
Combined sprays for allergic rhinitis maintenance
This meta-analysis looked at the reported efficacy for allergic rhinitis control of various topical sprays, particularly comparative studies. There were fewer ‘head to head’ studies than we would have hoped to exist. This review included intranasal anti-histamines, intranasal steroids and...
N-acetylcysteine may have a role in the protection of cochlear hair cells
Gentamycin is an aminoglycoside antibiotic which is widely used throughout the world, despite its ototoxic potential. It therefore seems wise to continue the search for accessible otoprotective agents. The aim of this study was to clarify the potential protective role...Intratympanic treatments for subjective idiopathic tinnitus
Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...Cochlear implants for children
The field of cochlear implants in children has expanded remarkably over 40 years. Elizabeth Tyszkiewicz reflects on success and current challenges and calls for a national review of outcomes for young adults who received their implants in childhood. Aleena is...
Blindness after orthognathic surgery
This is a case report and review of the literature of this rare, but well recognised alarming complication. The authors discuss the possible mechanisms, suggesting that it does not arise from a direct injury to the optic nerve and is...
Long-term outcomes after (adeno) tonsillectomy
Patient-reported outcome measures (PROMs) are used increasingly to fill an ‘evidence gap’ where healthcare rationing threatens particular treatments. Tonsillectomy is a long-established and effective treatment for recurrent tonsillitis and obstructive sleep apnoea (OSA) in children. The T-14 outcome measure examines...
Malignant craniopharyngiomas
Craniopharyngiomas are successfully managed with surgery and / or adjuvant chemoradiotherapy. The transnasal endoscopic route has become increasingly utilised in the management of these challenging tumours. This paper reviews 23 cases from the literature of the rarely reported malignant transformation....
