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Clonidine based vs Remifentanil based hypotensive anaesthesia in FESS
A study investigating the use of clonidine preoperatively in FESS surgery. A double blinded trial of 47 patients in Barcelona randomised into receiving clonidine (20 minutes preoperatively) versus Remifentanil (continuous infusion). Propofol and fentanyl were used for induction and then...
Controlling tinnitus
The absence of sufficient evidence for the use of integrated sound generators for the management of tinnitus led the authors to conduct a randomised blind clinical trial in which they compared the use of a conventional hearing aid with a...
One airway, one disease - not for everyone!
While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...The search for pharmacological treatments for hearing loss and tinnitus
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...Breakthrough tinnitus device Lenire available in three new clinics in Spain
Neuromod has announced that clinically proven tinnitus treatment device, Lenire, is now available in Malaga, Seville and Granada through partnership with medical technology distributor, TRUSBIN.
Four (more) ways to reduce turbinates
Setting aside the issue of when/if to reduce inferior turbinates, the issue of how to reduce turbinates is a never-ending story. This edition of rhinology carries two articles looking at this subject, both prospective randomised trials comparing two different methods...
Salivary gland blues…
Intravenous methylene blue is a well-described method to assist in intraoperative localisation of parathyroid glands. The technique does come with challenges as anybody will know who has had to run adjacent to a theatre-bound trolley to ensure that the infusion...Genetic discovery using animal models: presbyacusis
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm
Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...Neuromod advances multiple regulatory approvals to expedite Lenire’s global availability
Neuromod, the medical technology company that created the Lenire® tinnitus treatment device, has announced approval to the Medical Device Single Audit Program (MDSAP) and EU Medical Device Regulation (MDR) certification. Neuromod’s MDSAP certification follows a comprehensive audit verifying compliance with...Aspirin desensitisation for aspirin-exacerbated respiratory disease (AERD)
In this article, the authors describe the importance of identifying aspirin-exacerbated respiratory disease in patients with chronic rhinosinusitis refractory to standard medical treatment. This can then open the door to considering aspirin desensitisation treatment which, in their hands, has proven...
