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1439 results found

Clonidine based vs Remifentanil based hypotensive anaesthesia in FESS

A study investigating the use of clonidine preoperatively in FESS surgery. A double blinded trial of 47 patients in Barcelona randomised into receiving clonidine (20 minutes preoperatively) versus Remifentanil (continuous infusion). Propofol and fentanyl were used for induction and then...

Controlling tinnitus

The absence of sufficient evidence for the use of integrated sound generators for the management of tinnitus led the authors to conduct a randomised blind clinical trial in which they compared the use of a conventional hearing aid with a...

One airway, one disease - not for everyone!

While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...

The search for pharmacological treatments for hearing loss and tinnitus

Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

Breakthrough tinnitus device Lenire available in three new clinics in Spain

Neuromod has announced that clinically proven tinnitus treatment device, Lenire, is now available in Malaga, Seville and Granada through partnership with medical technology distributor, TRUSBIN.

Four (more) ways to reduce turbinates

Setting aside the issue of when/if to reduce inferior turbinates, the issue of how to reduce turbinates is a never-ending story. This edition of rhinology carries two articles looking at this subject, both prospective randomised trials comparing two different methods...

An otological cure for globus?

Globus pharyngeus is a common benign condition frequently encountered in ENT practice. Laryngopharyngeal reflux and psychological stressors are often considered to be contributory factors, but globus symptoms do not always respond to antacid medications. Such medications can also be limited...

Salivary gland blues…

Intravenous methylene blue is a well-described method to assist in intraoperative localisation of parathyroid glands. The technique does come with challenges as anybody will know who has had to run adjacent to a theatre-bound trolley to ensure that the infusion...

Vascular vertigo and dizziness: diagnostic criteria

This diagnostic criteria is one of the latest produced by The Bárány Society. It is a useful addition to previous ones for vestibular disorders. Vascular vertigo/dizziness by definition is caused by stroke, transient ischaemic attack (TIA), isolated labyrinthine infarction/haemorrhage and...

Anticoagulated patients and epistaxis

This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...