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ENT in this issue...The Future of ENT (Mar/Apr19)

Chris CoulsonENT Surgeon; Managing Director of endoscope-i E: chris@endoscope-i.com The future, predict it at your peril’, said me – just now. But despite this (rather late) warning, we have managed to commission five articles from futurists within our midst. The...

Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

BACO International 2018: Key Speakers

Prof Aldo C Stamm, MD, MSc, PhD Anatomy of the paranasal sinuses and skull base, and breaking the paradigms in severe spontaneous epistaxis It is a true honour to participate as an invited faculty member at the upcoming BACO International...

The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

Dizzy Me: Light on Balance

This book is unlike any academic text I have read before. It was not at all what I was expecting; the book aspires to be a “handbook for doctors [and a] guide for patients” but certainly takes an innovative, if...

How will our grandchildren view COVID-19?

Alan Johnson, known to our readers as the former President of ENT UK, gives us his thoughts on the COVID pandemic, looking at it through the lens of other health crises. As I write, COVID-19 is displacing almost all other...

Dizziness: confusion, issues and considerations

Douglas L Beck gives his unique take on the difficulties involved in diagnosing dizzy patients and the importance of well-founded research acting as the basis for any diagnosis and treatment decisions. Dizziness. Uh-oh. We really have a very limited understanding...

Bothersome ‘burping’ – speech therapy may help

Most people experience belching as a normal phenomenon, often after eating or drinking carbonated drinks in particular. However, separate to this normal physiological phenomenon, some people experience belches that can occur much more frequently (up to 20 times a minute)...

An alternative device for obstructive sleep apnoea

Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnoea (OSA), primarily due to the vast amount of short-term evidence in the medical literature it has accrued. The enduring obstacle to CPAP from becoming a treatment option...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...