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Cochlear implantation in SSD

There are currently several trials for cochlear implantation (CI) in single-sided deafness (SSD) being undertaken to answer some of the questions this paper from New York raises. Who is best suited to receive one? What are their outcomes and how...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Bile acids and pharyngeal malignancy

Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...

Identifying clinically useful salivary substitutes

This in vitro study analysed the efficacy of salivary substitutes used in the treatment of xerostomia following head neck irradiation. The researchers applied the products under evaluation onto a synthetic surface and onto cellular gingival models. The products were then...

Effects of nasal sprays on ciliary function

What do topical nasal sprays do to the nasal mucosa in the long term? This study reports the effect of corticosteroids, antihistamines and common preservatives in nasal sprays, benzalkonium chloride (BKC) and potassium sorbate (PS), on an in-vitro model of...

Virtual chromoendoscopy (VCE)

‘That’s a funny looking lesion on the larynx, it’s probably benign, but I should take a biopsy.’ Liz Ross and Ajith George discuss whether virtual chromoendoscopy will change this thought process. What are the origins and ENT applications? Traditional chromoendoscopy...