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IL-25 and nasal polyps, another target
Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
Identifying clinically useful salivary substitutes
This in vitro study analysed the efficacy of salivary substitutes used in the treatment of xerostomia following head neck irradiation. The researchers applied the products under evaluation onto a synthetic surface and onto cellular gingival models. The products were then...
Effects of nasal sprays on ciliary function
What do topical nasal sprays do to the nasal mucosa in the long term? This study reports the effect of corticosteroids, antihistamines and common preservatives in nasal sprays, benzalkonium chloride (BKC) and potassium sorbate (PS), on an in-vitro model of...Illuminating ear education: building interactive models to enhance inner ear understanding
Understanding the anatomy and function of the inner ear, particularly the vestibular apparatus and cochlea, is fundamental to audiology and otolaryngology education. However, the complex geometry and intricate functional relationships of these structures challenge us to find clear ways to...Are ENT patients who research their symptoms online better informed?
All our patients look up their symptoms online before they visit us, don’t they? And patients who do so are better informed than those who don’t, right? Well, that’s not actually the case… The ‘information era’ More information is now...
