You searched for "oropharyngeal"

574 results found

Retrospective review of paediatric salivary gland tumours

As is the case with adults, primary tumours of the salivary glands in children comprise a heterogeneous collection of different histological types. This paper presents a retrospective review of primary salivary gland tumours in children treated over the course of...

Active surveillance for papillary thyroid cancers – what is the risk of progression?

Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...

Adenoid cystic carcinoma – insights from a national database

Adenoid cystic carcinoma (AdCC) is a rare cancer of the salivary glands that accounts for approximately 1% of all head and neck malignancies. Hallmarks of this cancer type include a predilection for perineural infiltration, a prolonged clinical course with late...

Outcomes of reirradiation for recurrent head and neck SCC

Recurrent squamous cell carcinoma of the head and neck is often a challenge to manage when radiotherapy has previously been administered as a component of the initial treatment. Salvage surgery is usually the preferred modality of treatment, but for unresectable...

Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?

Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...

Canal cholesteatoma

This is a retrospective study of patients with external auditory canal cholesteatoma (EACC) managed at a single tertiary centre from 1 January 2010 to 1 January 2021. Ninety patients (100 ears) were included. Mean age at diagnosis was 56+23 years....

Office treatment for persistent rhinorrhoea

Vasomotor rhinitis (VR) is a common condition across the world. Patients suffering from VR commonly have symptoms of persistent bilateral rhinorrhoea, that can have a significant negative impact on their quality of life. Vasomotor rhinitis can be treated medically with...

Adjuvant radiotherapy for locally advanced (T3–4) major salivary gland cancer – survival benefits quantified

Complete surgical excision of major salivary gland cancers (MSGCs) is the current mainstay of curative treatment for this disease. Indications for postoperative radiotherapy according to current UK national guidelines include high-grade tumours, advanced-stage (stage 3–4) tumours, involved resection margins, perineural...

Polidocanol – a safer and equally effective alternative to ethanol for the treatment of thyroid cysts?

Percutaneous needle aspiration is a minimally invasive treatment option for thyroid cysts but suffers from a high recurrence rate (86% in 1 case series). This recurrence rate can be reduced substantially with the instillation of ethanol following aspiration. Ethanol instillation...

Transoral coblation surgery – a viable option for early laryngeal cancers involving the anterior commissure?

Transoral laser microsurgery is widely considered to represent the ideal treatment modality for early (T1a) laryngeal cancers. With disease involving the anterior commissure however, radiotherapy is often advocated on account of perceived superior voice and airway outcomes, plus potential difficulty...

Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease

Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...

Narrow band imaging in the management of carcinoma of unknown primary

This was a retrospective study to assess the utility of narrow band imaging (NBI) in the detection of a primary site in carcinoma of unknown primary (CUP). Patients with CUP who underwent transoral robotic surgery (TORS) and preoperative imaging with...