You searched for "therapeutics"

507 results found

Endovascular therapies for venous tinnitus

Tinnitus is an extremely vexing issue, not only for patients but also for otolaryngologists. The authors of this article review the causes of venous tinnitus, such as increased intracranial hypertension (IIH), dural venous sinus thrombosis and age-related anatomic variants. They...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Organoids in otolaryngology

This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...

ChatGPT to select patients for biologic therapies in CRSwNP?

This short communication describes programming the artificial intelligence (AI) algorithm for systematic review of current literature about guidelines on the clinical efficacy and safety of biologics in the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP). The authors first performed...

Elevated intracranial pressure versus migraines versus sinusitis?

This narrative review discusses the challenges faced by an otolaryngologist to differentiate elevated intracranial pressure (eICP), migraines and chronic rhinosinusitis (CRS). Facial pain, pressure, aural fullness, muffled hearing and tinnitus are often common symptoms described by patients with all three...

Prof ED Kitcher

Much has been said of the paucity of ENT Services in Africa [1]. Whilst Ghana has always been at the forefront of healthcare in Sub Saharan Africa, its ENT and allied services were somewhat suboptimal in the 1980s. This article,...

Supporting music listening through cochlear implant services – experience from a UK adult clinic on supporting musical engagement

The perception and enjoyment of music is central to many people’s lives. Harriet Crook (herself a cochlear implant recipient) tells us about important work in this area for people using hearing aids and CIs. There is now a wealth of...

Differing outcomes of three Sub-Saharan Africa journeys with the common goal of task sharing in audiology

Task sharing can be designed and implemented specific to the needs of each programme. Foundational principles of global health include developing local leadership as a means to successful sustainable service provision in low- and middle-income countries (LMIC) or regions. It...

Specialist teams deliver world-class trauma care

University Hospitals Birmingham NHS Foundation Trust runs the Queen Elizabeth Hospital Birmingham, which is a designated Major Trauma Centre. The Trust holds the contract to treat all UK injured military personnel evacuated from combat zones overseas. More than 1200 of...

Singing after laryngectomy: Shout at Cancer

Thomas Moors is an ENT junior doctor with a background in music and singing. Combining these interests, he has set up a charity to help patients who have had a laryngectomy. He has achieved considerable public attention, and he tells...

Differing outcomes of three Sub-Saharan Africa journeys with the common goal of task sharing in audiology

Task sharing can be designed and implemented specific to the needs of each programme. Foundational principles of global health include developing local leadership as a means to successful sustainable service provision in low- and middle-income countries (LMIC) or regions. It...

Charitable hearing care in Pakistan: establishing the IMRA Cochlear Implant Programme and Middle Ear Project

IMRA, the International Medical Relief Agency, is a registered charity providing volunteer-delivered cochlear implant and major ear surgery to children and adults in Pakistan. Established in 2001 by UK-based ENT surgeons led by Mr Haroon Khan, its primary aim is...