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COOL therapy for cisplatin-induced hearing loss
Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...Medical training initiative (MTI): stepping outside the box
Medical training initiative (MTI) scheme in the UK are becoming increasingly available and are actively supported by ENT UK. Despite this, knowledge of them is limited and there can be a mismatch between supervisors and potential candidates. Our authors, Manuela...A brief history of the acoustic ear trumpet and some collection favourites
If you think you know a thing or two about ear trumpets, I’d bet Michael Briggs knows more! In this fascinating article, he tells the history of the ear trumpet, as well as sharing some wonderful pictures from his Guiness...The astronomer’s nose: Tycho Brahe’s controversial prosthesis
Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....Wound moisture sensing in traumatic wounds
Wounds can be small and unpleasant, or may be large and life-threatening. The skin is a physical and an immunological barrier to infection, and any defect in the integrity of the skin may enable bacterial or fungal invasion. The successful...Innovative approaches to treating deafness
Shahar Taiber and Karen Avraham give us a summary of gene therapies for hearing loss, with an overview of limitations and what the future holds. Hearing loss is the most common sensory disorder. The last two decades have seen a...The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies
Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...
