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2531 results found

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Pituitary tumour associated headaches

This longitudinal cohort study presents data with significant clinical implications for patients with headaches and the clinicians and surgeons who treat them. For the study, patients completed a self-administered survey on headache characteristics on initial presentation and after surgery of...

Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Mitomycin in adjuvant treatment of laryngotracheal stenosis

Laryngotracheal stenosis (LTR) is a difficult condition to manage, and the effectiveness of surgical treatment is limited by the tendency of scar tissue to reform. Mitomycin has been used as a controversial adjuvant to surgical treatment for many years. Drawbacks...

Automated contouring of costal cartilage for pinna reconstruction – a proof of concept

Presently there are limited applications of automation within operative ENT. This proof-of-concept study explores the use of an augmented robot to contour cadaveric costal cartilage for auricular reconstruction. Ordinarily this task is performed manually. This takes considerable time due to...

Talking lasers – setting the stage for innovation in advanced ENT surgery

Offering leading consultants 25 years of excellence throughout the UK, Neomed is proud of its unsurpassed reputation across a legion of esteemed medical organisations.

Let’s talk lasers – setting the stage for innovation in advanced ENT surgery

Offering leading consultants 25 years of excellence throughout the UK, Neomed’s reputation across a legion of esteemed medical organisations is unsurpassed.

Poking the bear: learning to drain quinsy on a mannequin head

Simulation in medicine has gained significant traction in both undergraduate and postgraduate training over the last couple of decades or so – the benefits to all involved are clear. The airline industry models for human factors and crew resource management...

Working with people with hearing loss and dementia

A member of the SENSE-Cog team in the UK, Dr Littlejohn provides an overview of multidisciplinary recommendations for diagnosis, management and care of older adults with hearing loss, vision loss and dementia. She underscores how consideration of hearing status when...

Emergent surgical airway in head and neck conditions

This systematic review and meta-analysis looked at 1011 surgical airways in 14 studies. Of these airways, 50 were cricothyroidotomies. The mean complication rate was 16.8% with an airway-related mortality rate of 0.2%. They noted that the odds of complication significantly...

Endoscopic CSF leak repair using nasoseptal flap

Many of us during training or in established practice will have encountered the complication of anterior skull base CSF leak. This can be a challenging problem to deal with and in this article the authors describe their favoured approach. Cerebrospinal...

An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...