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OTO-104 in noise-induced and cisplatin-induced hearing loss

These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...

Cochlear implantation in SSD

There are currently several trials for cochlear implantation (CI) in single-sided deafness (SSD) being undertaken to answer some of the questions this paper from New York raises. Who is best suited to receive one? What are their outcomes and how...

Chemo-radiation in elderly patients with head and neck cancers

Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...

Is it really working? Assessment versus real-life language measures

Research in the field of language treatment and rehabilitation to date has used single-word naming as a controlled measure of outcome. Yet, given people do not actually communicate in single words, there is much debate as to whether this approach...

Management of single-sided deafness in adults: a bone conduction solution

Single-sided deafness (SSD) presents a limited number of methods for management, and not all of them meet the patient’s expectations. The aim of this article is to set out the available bone-conduction treatment methods for managing single‑sided deafness in adults....

Quick & Efficient Procedures with DTR’s Sterile Single-use Aural Care Range of Instruments

DTR Medical’s Single-use Aural Care Instruments have been carefully designed to assist in the restoration of hearing through a Hearing Aid when the mechanism becomes sclerosed or fused together.

Bipolar microdebrider turbinoplasty

There are a variety of ways to reduce the bulk of hypertrophied turbinates. Kimberley Lau and Showkat Mirza describe their technique which can be used in difficult cases and with minimal morbidity. As ever, one aim should be to avoid...

Which bit of our brains do we need to recognise fear, disgust and happiness?

Recognising other people’s emotions is a useful life skill for human interaction in both social and vocational situations. Yet there remains significant debate about which areas of the brain are required to enable us to read and understand these facial...

Current Trends in Implantation Otology

Priya Achar, Consultant Neurotologist, Nottingham University Hospitals NHS Trust, Nottingham, UK. Stalwarts in the field of implantation otology, including surgeons and audiovestibular scientists from the UK, Europe and the USA, attended this academic feast. Organised by Professor Laura Viani (below...

When should revision FESS leave you reaching for the script pad?

This very interesting work from the professorial team in London seeks to define a group of patients with CRSwNP who may benefit from early biological treatment since they are at risk of failure of surgical and conventional medical management. Approximately...

Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C

Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.