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Risk of second primary cancer among patients with head and neck cancers
Patients with head and neck squamous cell carcinoma (HNSCC) have an elevated risk of developing a second primary malignant neoplasm (SPMN). These are of increasing concern because the number of survivors of HNSCC has been growing owing to early detection...
A time-saving method for faster cancer diagnosis and treatment
One of the main impediments in achieving UK Government cancer diagnosis and treatment targets is lack of diagnostic capacity. An increase in head and neck cancers by 50% in the last five years has put on additional strain. In this...
A mouth-rinse test that can screen for oral cancer?
This paper presents a promising screening tool for oral cancer – using a simple chlorhexidine mouth-rinse. The hypermethylated ZNF582 and PAX1 markers were chosen based on previous studies using oral scraping methods of collection and have been shown to be...
Are there benefits of prophylactic swallowing exercises for patients with head and neck cancer?
This randomised controlled trial aimed to establish the impact of prophylactic swallowing exercises in patients undergoing chemoradiation therapy for head and neck cancer. The primary outcome was the functional oral intake scale (FOIS), although secondary measures for feeding tube use,...
Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...
Reconstruction of the Head and Neck: A Defect-Oriented Approach
This is the second Thieme book on head and neck cancer by this author that follows on from Head and Neck Cancer: an Evidence-Based Team Approach four years ago. It is a well-structured, up-to-date book in a readable layout with...
Work and the risk and carcinoma of the larynx
This is a census on the national cancer registry in France to detect professions at a higher risk of squamous cell carcinoma of the larynx. During the period 2001-2016 there were 244 registered cases of cancer of the larynx. Amongst...
Malignant transformation of leukoplakia in previous cancer patients
This is a retrospective study from Taiwan assessing risk factors in developing oral squamous cell carcinoma from surgically excised oral leukoplakia in patients with a previous oral cancer, the underlying thought being that patients with an oral carcinoma have a...
Perioperative management of the head and neck cancer patient
The perioperative care of patients with head and neck cancer is complex and requires significant preoperative planning and patient education. The issues include analgesia, antibiotics, stoma and wound care, general and chest physiotherapy, thromboprophylaxis and nutrition. This article provides a...
Delirium post-op
This is a retrospective study from Japan analysing 102 patients who underwent oral cancer resection and free flap reconstruction. Postoperative delirium occurred in a third of these patients. An increased risk was identified in those with high preoperative albumin, postoperative...
Lymph node ratio is a significant predictor for loco-regional recurrence after neck dissection in patients with papillary thyroid cancer
Lymph node metastases are common in papillary thyroid cancer (PTC), yet the impact of nodal metastases on survival remains unclear. Lymph node density (LND) is the ratio between the number of positive lymph nodes excised and the total number of...
