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The challenges in the risk stratification of thyroid nodules and cancers: the role of molecular testing

Around the world, molecular testing is becoming more widely used to personalise the management of thyroid nodules. Thyroid nodules are relatively common. They are palpable in ~5% of the population, while high-resolution ultrasound (US) incidentally finds them in 19–68% of...

In conversation with Jeff Small and Navid Shahnaz

The impact of COVID-19 has been felt on all levels of society and deeply affected our lives. It has challenged us to find new ways of carrying on with our activities at home, work, and school. Jeff Small, Director and...

In conversation with Jeff Small and Navid Shahnaz

The impact of COVID-19 has been felt on all levels of society and deeply affected our lives. It has challenged us to find new ways of carrying on with our activities at home, work, and school. Jeff Small, Director and...

New MRI technique assesses treatment response in skull base osteomyelitis

This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...

Interacoustics: Trends in Balance

I recently attended the 4th Annual Trends in Balance online course. Day one was optimizing the vestibular diagnostic test battery, day two looked at the functional balance assessments available and day three looked at vestibular rehabilitation.

Embracing the changes prompted by lockdown

March 2020 introduced the concept of lockdown to audiology services in the NHS, prompting a rethink of how to best provide hearing care. In this issue, we hear from Hanna Jeffery, a Clinical Scientist working at the Royal Glamorgan Hospital...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Hypopharyngeal Cancer

The 83rd book from the series by Advances in Oto-Rhino-Laryngology is another addition for the surgeon looking for an update in the management of hypopharyngeal carcinoma. The 180-page publication, divided into 16 chapters with 23 figures and 19 tables, has...

Management of necrotising otitis externa

Although uncommon, necrotising (previously malignant) otitis externa (nOE) can be very aggressive, particularly if not managed appropriately. In this study the authors perform a retrospective review of 25 patients admitted with nOE over a four year period at a tertiary...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

Active smoking predicts poor outcome in HPV positive oropharyngeal squamous cell carcinoma

Tobacco smoking is a well-known risk factor in human papilloma virus (HPV)-negative head and neck squamous cell cancer. Its effects include increased risk of treatment failure, distant metastases and reduced overall survival. HPV has been increasingly implicated as a causative...

Are we screening enough? Genetics in adult-onset sensorineural hearing loss

Sensorineural hearing loss (SNHL) in adults can be a result of multiple factors such as age, noise exposure and autoimmune pathology. In a group of patients, no cause is identified and the SNHL is treated as idiopathic. Authors evaluate the...