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Role of intranasal steroids after radiotherapy for nasopharyngeal carcinoma

Rhinosinusitis often follows radiotherapy in the treatment of carcinoma of the nasopharynx. The interval and severity may vary with the dose of radiation and stage of the carcinoma. In this randomised, controlled study, patients who developed rhinosinusitis after radiotherapy treatment...

Chronic rhinosinusitis and sleep

This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

To scan or not to scan?

This comprehensive review article seeks to establish how useful is MRI in the evaluation of patients with a history of smell loss or distortion. Interestingly, while some studies found the imaging unhelpful, one paper described found a 25% rate of...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

An effective treatment for post Covid-19 smell loss?

It is well understood that calcium levels in the nasal mucous affect the ability to smell, with higher levels having a negative impact, and some studies have shown increased calcium levels in patients suffering with Covid-19-related olfactory dysfunction. Calcium chelating...

Redeployment of audiologists during COVID-19

As the demand on intensive therapy units in the NHS increased, volunteers from the audiology profession stepped in to support colleagues. Here, they share their experiences of caring on the frontline. Redefining normal: from outpatients to the ICU By Emilee...

Less Than Full time Training in Otolaryngology

A recent Statement from the Association of Surgeons in Training (ASIT) stated that in 2011 there were 17 otolaryngology trainees in Less Than Full Time training (LTFT) [1]. Otolaryngologists in LTFT posts (17/151) is the largest group after general surgery...

Medical and surgical management of performing vocalists

Dr Steven Zeitels is widely recognised as the foremost laryngologist of his generation. He has been at the forefront of innovation for 25 years, and has treated innumerable high-profile singers, most recently Sam Smith and Adele. Here, he gives us...

Team based learning in speech language pathology graduate courses

According to the author of this article, the role of a speech language pathologist involves clinical problem solving in both diagnostic and treatment processes. Problem solving involves cooperative collaboration with clients and their parents. Therefore, in this pilot study, the...

Chronic rhinosinusitis update

There is still a lack of awareness of chronic rhinosinusitis (CRS) despite its burden, calling for events such as the recent Global Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Awareness Day. Research findings from recent publications by Backaert et al have...