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The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies

Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...

Sound advice for staying healthy: promoting holistic health in adults with hearing loss

Hearing loss is linked to chronic conditions like dementia and heart disease. Dr Maidment explores how integrated healthcare can improve outcomes, highlighting the need for a multidisciplinary approach. Emerging evidence suggests that hearing loss is associated with an increased risk...

From technology to humanity: a conversation on person-centred hearing care

With a career that has spanned continents and disciplines – clinical audiology, cochlear implant technology and global leadership – Mei Dingxiang Feng is now leading a movement to bring person-centred care (PCC) to the forefront of hearing healthcare. In this...

Giacomo Puccini’s laryngeal cancer

Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...

Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Acoustic shock: definitions and clinical aspects

Acoustic shock, a previously little-known and poorly understood clinical entity, came to the public’s attention in 2019 due to a high-profile legal case of a musician at the Royal Opera House. In this fascinating article, Andrew Parker and William Parker...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

A binaural detection task that reveals deficits in listeners having ‘slight’ or ‘hidden’ hearing loss

The association of degraded binaural processing in adults with clinically defined ‘slight’ or ‘hidden’ high frequency hearing loss is of great interest to clinicians if it can be measured. Leslie R Bernstein and Constantine Trahiotis share their findings in measurements...