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Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...

AOT President, Manish George, highlights the many issues COVID-19 has created for trainees

It is clear that COVID-19 has created multiple wide-reaching issues for trainees as a whole. Whilst an earlier preoccupation of mine has been to...

JLO Travelling Study Bursaries

The Journal of Laryngology and Otology is offering three generous travel bursaries in 2025, each to the value of up to £3000.

Mindfulness based approaches to tinnitus management: meditations on a new approach

Psychological approaches to tinnitus There is now widespread agreement that an individual’s interpretation of tinnitus can determine how distressing they find it. If tinnitus is regarded as non-threatening then habituation normally follows. If, however, tinnitus is interpreted as threatening, habituation...

Aspirin desensitisation for aspirin-exacerbated respiratory disease (AERD)

In this article, the authors describe the importance of identifying aspirin-exacerbated respiratory disease in patients with chronic rhinosinusitis refractory to standard medical treatment. This can then open the door to considering aspirin desensitisation treatment which, in their hands, has proven...

Mapping the nose – first spatial map of olfaction published

Scientists at Harvard Medical School have created the first detailed map of smell receptors in the nose, catching up with similar achievements in sight, hearing and touch. The map reveals that smell receptors are highly organised into tight bands based on type. The findings provide foundational knowledge needed to develop better therapies for loss of smell.

Combined sprays for allergic rhinitis maintenance

This meta-analysis looked at the reported efficacy for allergic rhinitis control of various topical sprays, particularly comparative studies. There were fewer ‘head to head’ studies than we would have hoped to exist. This review included intranasal anti-histamines, intranasal steroids and...

Argh! Facial pain! What to do??

We often come across patients with presentation of facial pain, but unless this is sinugenic in origin, our understanding and management of it can often be found wanting. Craniofacial pain is in fact highly complex and encompasses a wide range...

Stepwise approach to manage palatal myoclonus successfully

Palatal myoclonic tinnitus (PMT) is a rare condition caused by rhythmic voluntary or involuntary movements of the soft palate, mainly the tensor veli palatini and levator veli palatine muscles. Patients usually present with a ‘clicky’ noise in the ear. Oral...

Old age is hard to swallow

This article takes us through the diagnosis and management of swallowing problems common in older age. As our global population continues to grow and live longer, dysphagia will continue to be a global problem which needs to be recognised, understood...

Bell’s palsy – antivirals and steroids for all?

The role of antiviral medications in the treatment of Bell’s palsy remains somewhat controversial. Antivirals alone do not appear to be helpful, whereas numerous studies have shown that corticosteroids improve the chance of a full recovery compared to placebo. What...

Use of angular vessels in head and neck free-tissue transfer – a comprehensive preclinical evaluation

Free tissue transfer (FTT) has transformed the capabilities in head and neck reconstruction. Rotational and pedicled flaps are limited by the pedicle length, the type of tissue required and the size of the defect. FTT helps lessen the impact of...