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Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Superior semicircular canal dehiscence: transmastoid obliteration

Sometimes patients with dizziness turn out to have slightly more unusual causes of their problem. Thomas Milner and Georgios Kontorinis describe their technique for managing patients who have a diagnosis of superior canal dehiscence as an identified cause of their...

Audiology support for Philippine call centre employees

Call centre employees face unique challenges that impact their hearing health. BPO companies are implementing initiatives in the Philippines to safeguard their auditory wellbeing. The Business Process Outsourcing (BPO) industry in the Philippines is a dynamic and rapidly growing sector....

OBITUARY: Professor Vittorio Colletti (1943–2024)

After a long illness, Professor Vittorio Colletti, born in 1943, passed away on 2 January 2024 at the age of 80.

Audiology in this issue...Prevention

Alex Griffiths-Brown, BSc(Hons), MRes, Audiologist, The Shrewsbury and Telford Hospitals NHS Trust, Shrewsbury, UK. E: alex.griffiths-brown@nhs.netTwitter: @griffithsbrown1 'Prevention is better than cure’ is an adage that is attributed to the Dutch philosopher, Desiderius Erasmus, in around 1500. It is a...

3D printing and sustainability in audiology and ENT

As we try to avoid disposing of equipment that is still functional, we are challenged by company policies that make equipment ‘obsolete’ and no longer supported for repairs. One innovative solution is provided by 3D printing parts that are needed...

What’s hidden in hidden hearing loss?

In order to truly understand the many key aspects of acquired sensorineural hearing loss, the role of cochlear synaptopathy or ‘hidden hearing loss’ must be considered. Dan Guo and Sharon Kujawa review and summarise what we know to date, including...

Maturation of BC attenuation

The aim of this study was to clarify the reason for differences between bone-conduction hearing in adults and infants. The authors investigated how the sound pressure level in the ear canal changes depending on the bone-conduction transducer placement. By using...

Marshall Chasin: the harmony of music and audiology

Marshall Chasin, synonymous with the science of hearing and the art of music, discusses the techniques and technology he has employed over this career... so far. What’s the difference between your practice now and when you first started out? I...

Marshall Chasin: the harmony of music and audiology

Marshall Chasin, synonymous with the science of hearing and the art of music, discusses the techniques and technology he has employed over this career... so far. What’s the difference between your practice now and when you first started out? I...

Ear, nose and throat surgery in children – where will it be in 15 and 50 years?

Michael Kuo, David Albert and Mike Saunders have put their collective heads together to predict the future of ENT surgery in children; will there be a rise in workload due to increasing survival of children with complex medical problems? Or...