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2393 results found

Eosinophilic or not eosinophilic: dupilumab seems to work

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammation with interleukin (IL)-4, IL-13, and IL-5. Tissue eosinophilia in nasal polyps dramatically increased over a 10-20-year period. Classification of the severity of eosinophil status is expected to lead to...

Epithelial risk factors

This review paper from Barcelona retrospectively assesses patients diagnosed with oral epithelial dysplasia between 1995-2014 and followed up until 2017. In total, 144 cases were noted, of which 42% progressed to an oral cancer by the time of review in...

Benign positional paroxysmal vertigo manoeuvres in children and adolescents: a systematic review

In this paper of Saniasiaya et al, the literature review is conducted in accordance to the PRISMA consensus, aiming to investigate the outcomes of canalith repositioning manoeuvres (CRM) to treat benign paroxysmal positional vertigo (BPPV) in a paediatric and young...

Non-surgical and surgical management of arytenoids granuloma

Arytenoid granulomas are often a sequelae of laryngopharyngeal reflux (LPR). Unless there is suspicion of malignancy, they require a very balanced approach between conservative management and surgical intervention. The authors present a series of 62 patients with whom the primary...

Evolution of salivary gland pathology classifications

Targeted therapies for malignant salivary gland tumours have changed the treatment paradigm and therapy approaches. Better outcomes are now feasible. Choosing the treatment method requires a clear classification of the lesions. The authors of this paper reviewed the World Health...

Organoids in otolaryngology

This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...

Surgical variations in maxillomandibular surgery treating sleep apnoea

This is a scoping review further highlighting the success in curing sleep apnoea with a maxillomandibular complex advancement. The variations outlined are on East and Southeast Asian patients to reduce the aesthetic concern of bi-maxillary protrusion when large advancements are...

Neonatal nasal stenosis - conservative approach

The authors retrospectively evaluated the efficacy of heated humidified high-flow nasal cannula (HFNC) in neonates with nasal stenosis for this study. Of the six infants included in the study, five had congenital pyriform aperture stenosis. Three of these five also...

Cochlear implantation in inner ear schwannoma patients

Inner ear schwannomas (IES) are rare. Patients with IES tend to lose their hearing. Surgery is a treatment option, but it leads to complete loss of hearing. Other treatment options include stereotactic radiosurgery (SRS) and watchful waiting (WW). The authors...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Patient factors associated with spontaneous CSF leak

This article highlights the role of obesity, sleep apnoea and raised intracranial pressure as linked pathologies in the aetiology of the spontaneous cerebrospinal fluid (sCSF) leak. The authors link sCSF leak with obesity and comment on sCSF leak incidence increasing...

From battlefield to homefront: how the First World War shifted perceptions of deafness

The First World War marked a pivotal moment in the understanding and treatment of hearing loss and deafness. Prior to the war, deafness had been largely attributed to congenital causes. This view was influenced by a negative eugenic Darwinist ideology...