You searched for "therapeutics"
Gene therapy restores baby’s hearing
The guest editor of a forthcoming supplement for ENT & Audiology News has helped enable a baby girl born deaf to hear unaided for the first time.Optimising hearing aid solutions for tinnitus sufferers: essential factors to consider
A tailored approach combining counselling, sensory management and perceptual training can improve the effectiveness of hearing aids in managing tinnitus for individual patients. Hearing aids are useful tinnitus therapy tools, according to tinnitus management guidelines. However, there are few published...
Anticoagulated patients and epistaxis
This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...
A bittersweet finding
This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...
The many uses of human amnion
Human amnion has historically been the focus of much myth and superstition. To be born with the ‘caul’ intact was considered lucky and the caul was often manufactured into clothing. In 1910 foetal membranes were first used in skin transplantation...
Smell training is also effective in older patients
Olfactory loss is a common problem with a significant impact on quality of life. It has been demonstrated that olfactory training (OT) improves olfactory function in younger patients, but this study focuses in on patients aged 45 years and older....
Contemporary UK experience of oropharyngeal transoral laser microsurgery
It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...
The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...
