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International Journal of Pediatric Otorhinolaryngology cover image.

Further understanding of GJB2 hearing loss

9 November 2021 | | ENTA - Laryngology / Swallowing / Voice, ENTA - Otology, ENTA - Paediatrics
For many years, hearing loss has been an area which has attracted the interest of clinical and academic geneticists. Genetic testing for severe-profound hearing loss is now commonplace in many healthcare systems. Understanding the genetics of hearing loss has improved...

The structure and function of DNA

1 November 2014 | | ENTA - General, ENTA - Genetics
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...
B-Ent journal cover image.

Antioxidants for bacterial rhinosinusitis

10 March 2023 | | ENTA - Rhinology / Sinus
This Turkish laboratory animal-based study looked at the effects of alpha-lipoic acid on inflammation, oxidative status, and tissue integrity in an animal model of experimentally induced acute rhinosinusitis and to compare these effects with antibiotic treatment using cephalosporins. Alpha-lipoic acid...

Elasticated retraction in head and neck surgery – a trainee’s perspective

1 May 2017 | | ENTA - Head & Neck
The effectiveness of surgical technique and satisfactory outcome is greatly dependent on good surgical exposure. Retraction requires adequate traction and counter-traction of tissues in order to expose the tissue or organ under scrutiny for the surgeon. This is a universal...

Temporoparietal fascia flap for blind sac closure

4 March 2024 | | ENTA - Head & Neck
Chronic ear disease can be challenging to manage and difficult for patients to live with. In this article, the authors describe their technique for otomastoid obliteration and blind sac closure of the external canal allowing for a more tolerable situation...

Paediatric obstructive sleep apnoea

6 January 2023 | | ENTA - Paediatrics
As tonsillectomy rates for recurrent sore throats have declined, there has been increasing recognition of the importance of OSA in children. Not always diagnosed early – or in some cases at all – and with continuing debate as to how...

Genetic discovery using animal models: presbyacusis

1 November 2014 | | ENTA - Genetics, ENTA - Otology
By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

2 September 2022 | | ENTA - Audiology - Auditory Implants, ENTA - Audiology - Diagnostic, ENTA - Audiology - Adult, ENTA - Otology
Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

In conversation with Prof Helge Rask-Andersen: on cell regeneration and treatment of human deafness

2 September 2022 | | ENTA - Audiology - Adult, ENTA - Audiology - Diagnostic, ENTA - Audiology - Auditory Implants, ENTA - Otology
Helge Rask-Andersen, head of the inner ear research laboratory at the University of Uppsala in Sweden, has many achievements to his name. He was made an Honorary Member of ENT UK earlier this year. Gerry O’Donoghue caught up with him...

Lancet Commission on Hearing Loss

2 September 2022 | | ENTA - Audiology - Diagnostic, ENTA - Audiology - Adult, ENTA - Audiology - Auditory Implants, ENTA - Otology
The Lancet Commission on Hearing Loss was convened in 2019, and its main report will be published in 2023. We learn more about it here. The Lancet Commission on Hearing Loss was convened in 2019, and was charged by Richard...

The search for pharmacological treatments for hearing loss and tinnitus

1 November 2016 | | ENTA - Audiology - Adult
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

Laryngology: past, present and future

1 May 2018 | | ENTA - Laryngology / Swallowing / Voice
Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...