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Recurrent ENT infections in children – is it a sign of primary immunodeficiency disease?

ENT clinicians often come across children with recurrent ear, sinus and pulmonary infections. These recurrent infections, albeit common in childhood, can represent an early sign of primary immunodeficiency diseases (PIDD). PIDD is an underdiagnosed group of genetic disorders involving absent...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Prednisolone and/or acyclovir for Bell’s palsy

Landmark Paper: Sullivan FM, Swan IRC, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell’s Palsy. N Engl J Med 2007;357(16):1598-607. Facial nerve paralysis as a consequence of Bell’s palsy can result in devastating long-term effects on...

Why and how I enjoy the history of Otorhinolaryngology, Head and Neck Surgery (OHNS)

In the first article of this History of ENT edition, Albert Mudry explains why history is so intrinsically relevant to the practice of medicine and tells us how to use history as a foundation for the discovery of new ideas,...

Development of a new negative-pressure ventilatory support device: Exovent

The pandemic has driven innovation in ways that we have not seen for many decades. Intensive care medicine and ENT have been at the forefront of these advances, and our good friends David Howard (never one to put his feet...

World Health Assembly adopts a resolution on hearing loss: a defining moment for the global hearing health community

The World Health Assembly recently adopted a resolution on hearing loss. In this article Shelly Chadha and Alarcos Cieza outline how the resolution came to be and how the World Health Organization and its partners plan to implement it. The...

Secrets of the listening brain: what measuring the brain can tell us about hearing aid use and more

In a typical audiology clinic, on any given day, a person is waiting to see an audiologist to get a hearing aid (HA). It might have taken over 10 years to get to this point of considering a hearing aid(s)...

Brussels, a multicultural city with varied ENT practice

Brussels has a proud history in the world of ENT. Jérome Lechien, who is on the Communications Committee for the CEORL-HNS 2019 Congress, and Daniele de Siati, a member of the international Scientific Committee, give us a history lesson and...

Audiology in this issue...New Landscapes in Audiology

Keiran Joseph, Clinical Lead, Evelina London, Children & Young People’s Audiology Centre, Guy’s & St Thomas’ NHS Foundation Trust, UK. E: Keiran.Joseph@gstt.nhs.uk Over the past year, the world of audiology has changed faster than ever before. The COVID-19 pandemic has...

BAA to host World Congress of Audiology in 2028

The British Academy of Audiology is delighted to have won its bid to host the International Society of Audiology’s World Congress in 2028 (WCA2028). The 38th Congress will be hosted in Edinburgh, 23-26 April 2028.