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Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Imaging in hyperparathyroidism

Following their caudal migration at eight weeks of development, the parathyroid glands normally locate posterolaterally to the upper pole of the thyroid gland at the level of the cricoid cartilage (superior parathyroid glands arising from the fourth branchial pouch and...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Progress of head and neck surgery in China over the last 20 years

Although China was late to establish head and neck surgery in comparison to other areas of oncological surgery, with the persistent hard work of head and neck surgeons nationally, it has progressed significantly during the last two decades. Yueying Ma...

Cochlear implants: recipient stories

The most powerful evidence for the remarkable achievements made with cochlear implants over 40 years comes from the life-changing, personal stories of those who have benefited from the technology. James Rylance I first noticed a problem with hearing when I...

Rhinoplasty for cleft nose deformity

Modern cleft lip and palate repairs produce excellent functional and aesthetic results at an early age. Tony Holmes, a craniofacial surgeon with over 40 years’ experience, shares his wisdom on the best timing and techniques for addressing the associated complex...

In conversation with Jane Lea: the journey from athlete to surgeon

Dr Jane Lea is a clinical professor and fellowship director of otology and neurotology at the University of British Columbia. Prior to becoming a doctor, Jane was a semi-professional footballer and represented Canada. As a result of three knee operations,...

Music and cochlear implants

Introduction The introduction of multichannel cochlear implants (CIs) in the early 1980s provided children and adults with severe and profound hearing losses with greatly improved speech perception skills. In this paper, however, I am going to focus on an area...

Commentary: dementia, hearing loss, and the danger of professional rabbit holes

The Lancet, a world-leading general medical journal, has a global impact. Its commissioned report into dementia prevention, intervention and care has been cited over 6000 times and has further been reviewed and updated in 2020 and now 2024. Here, Profs...