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Fungal rhinosinusitis

Allergic fungal rhinosinusitis (AFRS) has been defined by the following characteristics: presence of nasal discharge, nasal obstruction, decreased sense of smell or facial pressure for 12 weeks, mucin within the sinus cavity containing fungal hyphae and degranulating eosinophils, endoscopic evidence...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

Performing ethnic aesthetic rhinoplasty

This article reviews principles of performing rhinoplasty in non-Caucasian patients, exploring patient expectations based on differences in race, ethnicity and culture. One of the main challenges is a lack of well-established ideal facial measurements for different non-Caucasian groups. The authors...

Role of maxillary sinus irrigation as an adjuvant to current management of chronic rhinusitis without polyposis

Several decades have passed since irrigation of maxillary sinuses generally became a treatment of the past. A more recent concept of biofilms may have evoked new interest in this past procedure, fraught with its own issues. In this study, the...

Choose Experience. Choose Expertise. Choose BenCorpp®

BenCorpp® is more than just a company - it is a family-owned business located in Mirandola, a small town in northern Italy, known worldwide as “the Biomedical Valley of Europe”.

Medical training initiative (MTI): stepping outside the box

Medical training initiative (MTI) scheme in the UK are becoming increasingly available and are actively supported by ENT UK. Despite this, knowledge of them is limited and there can be a mismatch between supervisors and potential candidates. Our authors, Manuela...

The Graham Fraser Foundation

Graham Fraser (1936-94) was a pioneering otolaryngologist, in whose memory the Graham Fraser Foundation was set up, and an eponymous annual lecture and a travelling fellowship in otology were established. It’s an honour to profile the Foundation in this extended...

Audiological approach to treatment of blast-induced tinnitus

Hearing loss and tinnitus resulting from blast waves in the war zone is becoming more common in our clinics. Hamid Jalilvand based in Tehran, shares his experience in audiological rehabilitation and research findings on patients in his clinics with a...

Physician health and wellness amidst a global pandemic

Dr Westerberg attended a workshop on Physician Wellness hosted by Dr Osler a few years ago at our Canadian Society of Otolaryngology-Head and Neck Surgery meeting. The list of symptoms of stress and burnout resonated as typical of almost a...

Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Anaesthesia under fire

Kate Prior is an anaesthetist who has, quite literally, been there, done that. In this article she manages to use words on a page to bring to life some of the conditions and challenges she faced as a member of...