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Thyroid nodules – time for a rational imaging approach
“The more you know, the harder it is to take decisive action. Once you become informed, you start seeing complexities and shades of gray. You realize that nothing is as clear as it first appears. Ultimately, knowledge is paralyzing.” Calvin,...Neurological idiopathic disease: a shared journey for NASA and medicine
Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...Inspired by Ida: In conversation with Lise Lotte Bundesen, Managing Director of the Ida Institute
The Ida Institue takes a collaborative approach to developing tools and resources that can be used by clinicians around the world to improve person-centred care. Their Managing Director Lise Lotte Bundesen tells us about their newest project, Inspired by Ida,...
A bittersweet finding
This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...A ‘rye’ tail – the fatal illness of Lord Boringdon, a Regency tragedy
The anonymous privately-printed book, Some Account of Lord Boringdon’s Accident, describes in deferential terms a case of aspiration of a foreign body and its sequelae. Today aspirated foreign bodies are serious but curable injuries; before the invention of the bronchoscope...Could social isolation be a factor in the link between hearing loss and dementia?
In 1802, Beethoven wrote to his brothers Carl and Johann about his hearing loss: “You men who think or say that I am malevolent, stubborn, or misanthropic, how greatly do you wrong me. You do not know the secret cause...Harnessing head and neck cancer genomics for personalised medicine
Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...The Ewings and paediatric audiology
Medical historian, Laura Dawes, discusses how Irene and Alexander Ewing were instrumental in shaping paediatric audiology in the first half of the 20th century. Irene and Alexander Ewing were the power couple of audiology in the UK in the mid-20th...
Post-operative tonsillectomy bleeding with a normal clinical exam
Tonsillectomy is amongst the most common surgical procedures performed across the western world. For patients who report bleeding post-tonsillectomy, but have no clinical findings on examination, the management can be unclear. The accepted current management in most centres would be...
Polysolmnography and laryngomalacia severity
Laryngomalacia represents the single most common cause of stridor in infants. Most cases are self-resolving, but a proportion of children will require surgical intervention. This group aimed to analyse the efficacy of polysomnography in determining the severity of laryngomalacia in...
Time to endoscopic sinus surgery and outcomes
A well written prospective study, which demonstrates that patients who require endoscopic sinus surgery, should be operated on without long delay since this achieves better and more sustained outcomes. There were 1493 patients undergoing primary nasal surgery who had completed...
