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Spasmodic dysphonia – is greater awareness needed?
Spasmodic dysphonia (SD) is a focal dystonia of the laryngeal musculature. Previously considered to be a rare disorder, it has more recently been suggested that SD is in fact not rare but is frequently misdiagnosed or undiagnosed. This paper would...OAEE UPDATE - Urgent Call for Surgical Supplies in Ukraine
UK professionals have called for aid in sending surgical equipment to Ukraine during Russian invasion.Targeting the microbiome in chronic rhinosinusitis
Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...ENT in this issue...Anaesthetics and ENT
Nick Crombie, BMedSci BMBS FRCA FIMC RCSEd RCPathME, Associate Medical Director (Governance); Consultant Trauma Anaesthetist; Honorary Researcher, National Institute for Health Research SRMRC: Clinical Lead for Resuscitation Services, QEHB, UK. E: Nicholas.Crombie@uhb.nhs.uk Plastic surgeons think we do endless crosswords. Orthopaedic...Tonsillitis and tonsillectomies: where do we go from Paradise?
Landmark Paper: Paradise JL, Bluestone CD, Bachman RZ, et al. Efficacy of tonsillectomy for recurrent throat infection in severely affected children – results of parallel randomized and nonrandomized clinical trials. N Engl J Med 1984;310(11):674-83. The Paradise paper on tonsillectomy...Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...
Biologics for deafness
Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....
Precision medicine in allergic rhinitis and chronic rhinosinusitis
Precision medicine (PM) with its ‘four Ps’ (personalised, predictive, preventive and participatory) is about appreciating differences between individuals when offering management options for health problems. Multiple groups interested in rhinology such as EPOS and ARIA supported a review of the...
What blood tests should be requested to investigate vocal cord paralysis?
Patients who are discovered to have a vocal cord palsy with no obvious cause on history or examination routinely undergo investigations to exclude an underlying pathology. Cross-sectional imaging of the relevant recurrent laryngeal nerve is required, but considerable variability has...
The stubborn polyp cases are ‘different’
The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
