You searched for "molecular"

318 results found

Otolith dysfunction in congenitally deaf adults

This paper helps to further define the profile of ocular and cervical vestibular-evoked myogenic potentials (o and c VEMPs) in patients with congenital profound sensorineural hearing loss (PSHL). It highlights the prevalence of otolith (saccular and utricular) dysfunction that exists...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

In conversation with George Tavartkiladze

For decades, Professor Tavartkiladze has been the personification of Russian audiology and its best known ambassador on the international stage. Hailing from the republic of Georgia, he has led countless seminal initiatives within Russia to advance the science and practice...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....

In Memory: An Interview with Professor Leslie Michaels

The Memorial Service for Professor Leslie Michaels takes place next week (mid-April 2019). Professor Michaels was the former Professor of Pathology at the Institute of Laryngology and Otology at UCL and The RNTN&E Hospital. His inspirational achievements are worthy of...

Is bone cement a cost-effective solution?

This study looks at the functional results of 52 patients who underwent bone cement ossiculoplasty. Patients were divided into four groups based on ossicular disruption. Group 1 (30 patients) had lenticular erosion only. Group 2 (13 patients) had absent incus....

In this issue...Inner Ear Therapeutics

Emma Stapleton, MBChB, FRCS (ORL-HNS), Consultant Otolaryngologist, Cochlear Implant and Skull Base Surgeon, Manchester Royal Infirmary, UK. E: emmastapleton@doctors.org.ukTwitter: @otolaryngolofox Ralph Holme, Director of Research and Insight, RNID, UK. Ralph. E: Holme@rnid.org.uk W: www.rnid.org.uk For Mar/Apr 2022, we sang the...

From the editor Jan/Feb 2025

Declan Costello, MA, MBBS, FRCS(ORL-HNS),Consultant Ear, Nose and Throat Surgeon, Wexham Park Hospital, Slough, Berkshire, UK. E: d.costello@nhs.netTW / X: @Voicedoctor_uk As we slip seamlessly into the new year, I hope you have all had a good break and that...

18th National ENT Masterclass®

Back to where it all started 20 years ago: (L-R) Prof Shahed Quraishi, Mr Kevin Gibbin, Prof Patrick Bradley, Prof Anshul Sama and Prof Nick Jones. E Tian Tan, ST4 Otolaryngology, Royal Hallamshire Hospital, Sheffield, UK. It was inspirational to...

Tonsillitis and tonsillectomies: where do we go from Paradise?

Landmark Paper: Paradise JL, Bluestone CD, Bachman RZ, et al. Efficacy of tonsillectomy for recurrent throat infection in severely affected children – results of parallel randomized and nonrandomized clinical trials. N Engl J Med 1984;310(11):674-83. The Paradise paper on tonsillectomy...

Loss of smell after COVID-19: a view from the patient forums

Patient advocate, Chrissi Kelly, founder of AbScent, talks about how the pandemic has changed the way we think about smell loss. The high prevalence of chemosensory impairment as a result of the SARS-CoV-2 virus has shone a much-needed spotlight on...