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IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Organoids in otolaryngology

This interesting review article summarises the status as well as future prospects of organoid technology in our field. Organoids are a mass of cells which are typically cultured in vitro with 3D technology. They simulate miniature tissues and organs and...

The vestibular system is not immune to chronic otitis media

It is well recognised that chronic otitis media (COM) is a risk factor for sensorineural hearing loss. Studies on the effect of COM on vestibular function have been beset by design biases. The authors designed a case control study to...

Posturography in persistent postural-perceptual dizziness (PPPD)

Those in neuro-otology practice will be familiar with PPPD now appearing in the forthcoming beta edition of ICD-11. This condition combines the symptoms of phobic postural vertigo and chronic subjective dizziness in which anxiety plays a part. The underlying hypothesis...

IFOS 2026 – Istanbul

There was much celebration from the Turkish contingent at IFOS 2023 in Dubai where it was announced that Istanbul will be the destination for IFOS 2026. The Istanbul bid won by a landslide, picking up 61% of the vote and...

Outcomes in rhinosinusitis

This review goes through the various different ways of assessing outcomes and describes the pros, cons and limitations of each. The different methods are described in the context of guidelines in diagnosis and management and compared with other conditions such...

A new treatment for septal perforations?

Nasal septal perorations are notoriously difficult to close surgically and can be extremely symptomatic and debilitating for the patient. This paper describes the use of carvacrol (a monoterpene phenol of the family Lamiacaea which is often found in essential oils)....

Hearing healthcare in India

With a population of more than a billion people, and an estimated prevalence of hearing loss of somewhere between 5.9% and 16.5%, depending on which definition you use, India has a significant number of hearing impaired individuals. They are served...

How trainees can make major contributions to practice

At a time when many of our trainees feel poorly supported and disheartened, the formation of a National ENT Trainee Research Network (Integrate) has been a major advance, enabling them to develop and execute research projects directly relevant to clinical...

In conversation with Prof Peter Friedland – Reflections on an extraordinary career and life

Our illustrious friend, Harvey Coates, hears about Professor Friedland’s amazing personal journey, ranging from horrifying exposure to violence through to his clinical care for (and friendship with) Nelson Mandela and his prevailing passion for teaching. Professor Peter Friedland. Professor Peter...

Promoting human rights of deaf communities in low-resource settings

Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...

Promoting human rights of deaf communities in low-resource settings

Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...