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Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Neural plasticity and aural rehabilitation

Neural plasticity refers to an ability of the brain and central nervous system to change their structure and function or their reorganisation in response to environmental cues, experience, learning, behaviour, injury and / or diseases and treatments. Neural plasticity is...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

History of innovation in ENT

Innovation seems to have been in the strapline of every meeting, conference and course for the last few years. You would be forgiven for thinking it is a new a concept, but as Neil Weir beautifully details, innovation has been...

An office procedure to close small tympanic membrane perforations

Various methods have been described for closure of small tympanic membrane perforations, ranging from paper patching to use of fibrin glue. The procedure needs to be non-invasive and cost effective. Use of Terdermis to close perforations of all sizes has...

Hearing Conservation: In Occupational, Recreational, Educational, and Home Settings (1st edition)

Hearing Conservation was released in September 2011 by Vishakha Rawool, Professor of Audiology at West Virginia University. The book is intended for audiologists, researchers and graduate level students, as well as other professionals working in the fields of hearing conservation...

Sialendoscopy assisted excision of parotid stones

This is a retrospective paper from China that looks to assess the efficacy and safety of sialendoscopy with a combined transoral or transcutaneous approach for the removal of parotid stones. Sialolithiasis is known to be a cause for obstructive parotid...

Role of potassium channel opener in salicylate induced tinnitus

The exact mechanism in the origin of tinnitus is not known. Many pharmacological agents have been tried to to treat tinnitus without great success. Aspirin is a commonly used medicine in the elderly population to reduce the risk of stroke...

Coblation for laryngeal granulomas

Laryngeal granulomas remain notorious for their tendency to recur after surgical removal. Although high rates of complete remission have been reported with use of the potassium-titanyl-phosphate (KTP) laser, this equipment is expensive and not available in all units performing ENT...

‘Acoustic shock’

Development of hearing loss due to traditional and steady state noise in working environments has well defined medical, physical and legal implications in the present times. Organisations not complying with ‘Noise at Work Regulations 1989’ are liable for compensation if...

What we need to know about the new frontier of inner ear therapies

This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...

Voice change after total thyroidectomy with intact laryngeal nerves – a common but temporary problem

It has been reported that up to 87% of patients have a degree of voice dysfunction after thyroidectomy, even when the laryngeal nerves are preserved. Postoperative inflammation, laryngeal oedema due to vascular congestion, direct damage to the cricothyroid muscles and...