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Clinical pathological features associated with malignant change in oral leukoplakias

This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...

Sinonasal inverting papilloma and HPV - a meta-analysis of recurrent tumours

Sinonasal inverting papilloma (SNIP) is a common benign tumour of the sinuses. Difficulty lies in the association with metachronous or synchronous SCC of the sinus and also in the complete removal of the lesions due to their anatomical location. An...

Surgical management of refractory osteoradionecrosis

This is a French single-centre, 10-year experience of 55 surgical resection and reconstruction procedures. They claim an overall effectiveness rate of 92.3%. A total of 36 segmental and 19 marginal mandibulectomies were performed. A variety of free flaps were used,...

Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?

Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....

Malignant transformation of leukoplakia in previous cancer patients

This is a retrospective study from Taiwan assessing risk factors in developing oral squamous cell carcinoma from surgically excised oral leukoplakia in patients with a previous oral cancer, the underlying thought being that patients with an oral carcinoma have a...

Should all patients with BPPV have an MRI?

This paper describes an interesting series of 500 patients over a 10-year period with posterior canal BPPV, who had been investigated with MRI. The female to male ratio was 1.6:1 with a mean age of 56. There was a right...

Surgical and non-interventional management of laryngomalacia

In this elaborate review article, the authors have described various aspects of laryngomalacia and its surgical management with supraglottoplasty or otherwise, gleaned from an extensive review of the literature which provided evidence or the lack of it in relation to...

EMG and unilateral vocal fold palsy

The authors studied the diagnostic and prognostic value of laryngeal electromyography (LEMG) in adults with unilateral vocal fold palsy. The study included 61 patients who were tested on average seven months after their palsy (4-11 months). In most cases the...

Comprehensive Management of Skull Base Tumors – Second Edition

This is the second edition of a multi-author textbook first published over a decade ago. Most of the chapter authors are North American, as are the editors themselves. There is also a smattering of well-known contributors from the rest of...