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A review of topical treatments for chronic rhinosinusitis

Topical nasal treatment is considered the mainstay treatment for chronic rhinosinusitis (CRS). The authors reviewed the effectiveness of saline irrigation, topical corticosteroids, topical antibiotics and topical antifungals in the treatment of CRS. Large volume saline irrigation was found to be...

Reduction in recurrent cholesteatoma rates with bony obliteration tympanoplasty technique

This large retrospective study from the Erasmus Medical Centre in Rotterdam compares outcomes in traditional canal wall up (CWU) and canal wall down (CWD +/- partial obliteration of mastoid bowl) mastoid surgery for cholesteatoma with bony obliteration tympanoplasty (BOT, which...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

Cognitive function is preserved in episodic vestibular disorders

Cognitive deficit in bilateral vestibular failure in particular, but also in unilateral vestibular failure, is well documented. The authors designed this prospective study to determine if deficits in cognition, as well as anxiety and depression, were present in episodic vestibular...

Radiology of referred otalgia

Otalgia is a common presenting complaint to Ear Nose and Throat Departments. Otalgia is either primary or secondary (referred) [1]. Referred otalgia is a ‘red flag’ symptom and can be a diagnostic challenge for clinicians and radiologists as the pathology...

Patient and public involvement in research

One step further from involving patients in setting research priorities is to involve them in the planning and recruitment stages of the subsequent trials and studies. Here, Carl Philpott and Aneeka Degun explain the concept of Patient and Public Involvement...

The James Lind Alliance – involving patients and their health professionals jointly in setting priorities for research

In a world of patient-reported outcomes and patient-centred care, patient-centred research must also be considered. That is where the James Lind Alliance (JLA) comes in, as Caroline Whiting explains below. Through Priority Setting Partnerships (PSPs), it allows patients, their carers...

Pre-clinical development of magnetic delivery of therapy to middle and inner ears

Why are we developing this technology? A key problem in drug delivery is getting the therapy to the right place in the body, which is especially challenging for targets that are small, deep and are protected or surrounded by anatomical...

Outcomes of temporal bone-resurfacing for pulsatile tinnitus associated with vascular wall anomalies

This month’s Ed’s choice is an interesting systematic review into the management of pulsatile tinnitus. There are impressive results from resurfacing of symptomatic anatomical abnormalities of the temporal bone and I suspect that referrals for further imaging and otology clinic...

The ENT operating theatre viewed down the retrospectoscope

We learn much of our future by looking at our past; Douglas MacMillan provides us with a fascinating glimpse into his years as a junior doctor. The operating theatre was a somewhat alien environment in the late 1960s: theatre sisters...

Recovery rates in sudden sensorineural hearing loss

Sudden sensorineural hearing loss (SSNHL) is most commonly idiopathic, and is seen relatively frequently in ENT practice. Recovery spans a period of around 1-2 months, and ultimate outcomes are highly variable, from complete recovery to no detectable hearing. Although the...

Effects of nasal sprays on ciliary function

What do topical nasal sprays do to the nasal mucosa in the long term? This study reports the effect of corticosteroids, antihistamines and common preservatives in nasal sprays, benzalkonium chloride (BKC) and potassium sorbate (PS), on an in-vitro model of...