You searched for "therapeutics"

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Getting to grips with acoustic trauma

Our understanding of hearing loss caused by noise exposure to those in the armed forces is growing in interest and understanding. Research at a cellular level is essential to increase our understanding so that we can better diagnose, manage and...

Chronic cough hypersensitivity syndrome

We all have patients who give us a ‘heartsink’ feeling; for many of us, the coughing patient is exactly such a situation. In this overview, Bhaskar Ram and Sangeeta Maini outline their approach to diagnosis. Declan Costello, Editor. Introduction Chronic...

Anticoagulated patients and epistaxis

This systematic review looks at the increasing complexity in this space as anti-thrombotics become more sophisticated and move away from the more well understood management of warfarinised patients. After a thorough search, 29 papers were found to be relevant and...

The many uses of human amnion

Human amnion has historically been the focus of much myth and superstition. To be born with the ‘caul’ intact was considered lucky and the caul was often manufactured into clothing. In 1910 foetal membranes were first used in skin transplantation...

Smell training is also effective in older patients

Olfactory loss is a common problem with a significant impact on quality of life. It has been demonstrated that olfactory training (OT) improves olfactory function in younger patients, but this study focuses in on patients aged 45 years and older....

A bittersweet finding

This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...

The hippo and the nose

Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...

Contemporary UK experience of oropharyngeal transoral laser microsurgery

It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...

Cell therapies for hearing loss

Cell therapies could offer a way to repair damage to the auditory system and reverse many types of hearing loss. This article looks at the progress being made.

Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

Save the date: WCA 2024

The 36th World Congress of Audiology is taking place in Paris, 19–22 September 2024. The organisers have released a teaser video to encourage audiologists to attend a cutting-edge conference where diagnostic and therapeutic innovation, personalised medicine and translational research will...

The potential benefits of having supervision in clinical practice

Marie Wardle is the Programme Director of the Interpersonal Therapy department in the West Midlands, UK and part of her role is to deliver supervision training courses for therapists in the region. Therapists, whether supporting patients with psychological or physical...