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Incidental thyroid nodules: should we observe or operate?
Thyroid nodules are extraordinarily prevalent, detected by physical examination in 7% and by imaging studies in 67% of the population. Although most of these nodules are benign, up to 20% are found to be malignant on excision. It’s a very...Thyroid nodules – time for a rational imaging approach
“The more you know, the harder it is to take decisive action. Once you become informed, you start seeing complexities and shades of gray. You realize that nothing is as clear as it first appears. Ultimately, knowledge is paralyzing.” Calvin,...
Expanding the role of FNA in thyroid nodule decision-making
Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...Thyroid dysfunction and Meniere’s disease: is there a relationship?
The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...
No increase in papillary thyroid cancer during pregnancy
This small study of 19 pregnant patients, who were diagnosed with papillary thyroid cancer before or during the early stages of pregnancy (up to 20 weeks), assessed the changes of thyroid tumours during pregnancy. Conducted at a single centre over...
Extent of central neck dissection in the patients with thyroid carcinoma
The first level of lymphatic spread in well-differentiated thyroid carcinoma is to the central compartment of the neck, namely, the paratracheal, prelaryngeal and pretracheal lymph nodes. Central neck dissection may carry an increased morbidity, namely, hypoparathyroidism and recurrent laryngeal nerve...
Surgery of the Thyroid and Parathyroid Glands - Third Edition
Surgery of the Thyroid and Parathyroid Glands - Third Edition is an excellent text for trainee and specialist surgeons with an interest in head and neck endocrine surgery. The organisation of the book simply makes sense, showing progression from the...
Variability in the management of differentiated thyroid cancer (DTC)
This retrospective study analyses for the first time the management planning of thyroid surgeons across the specialties. A questionnaire was sent to members of ENT-UK, the British Association of Endocrine and Thyroid Surgeons, Association of Surgeons of Great Britain and...
Clinicopathological features of follicular variant of papillary thyroid carcinoma
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...
Lymph node metastases in papillary thyroid cancer
This retrospective Korean cohort study looked at the risk factors associated with bilateral lateral lymph node metastases in patients with unilateral papillary thyroid cancer. There were 11 patients who met the inclusion criteria across an 11-year period from 2009 to...Surgical challenges in advanced or recurrent thyroid malignancy
The management of thyroid malignancy and extent of surgery is controversial, especially considering the limitations of preoperative diagnosis. Neil Tolley provides guidance and reminds us of our responsibility not to over-treat. In the UK, 16% of thyroidectomies are performed for...
