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Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

2020 Unmasked: Hidden strengths and vulnerabilities laid bare - By Joseph Sinnott

Masks were everywhere in 2020. The most visible to stop the spread of COVID-19 but others concealed soon-to-be revealed strengths and weaknesses. In April 2020, the UK Prime Minister was taken to intensive care suffering with this new and frightening...

Globe Trotting and 62 years of ENT

Vasant Oswal was, for many years, ‘Mister ENT’ in the Northeast of England. Appointed as a consultant to the old North Riding Infirmary in 1970, he led what was a small and little-known department through a period of tumultuous change...

ENT leadership

Challenges The first challenge is to agree what we mean by the term leadership because there are many different ways in which the term is used. What is, however, a consensus is that the key distinction between leadership and management...

Andreas Wagner: ESPO 2025 keynote speaker

The keynote speaker for ESPO 2025 in Stuttgart is renowned evolutionary biologist and author Professor Andreas Wagner, from Zurich. Prof Wagner will focus on the congress theme of ‘Innovation’, giving us his unique perspective on how evolution drives human creativity....

Andreas Wagner: ESPO 2025 keynote speaker

The keynote speaker for ESPO 2025 in Stuttgart is renowned evolutionary biologist and author Professor Andreas Wagner, from Zurich. Prof Wagner will focus on the congress theme of ‘Innovation’, giving us his unique perspective on how evolution drives human creativity....

BACO – the early years

The origins of the British Academic Conference in Otolaryngology (BACO) are indelibly intertwined in the mists of time with the foundation of the British Association of Otolaryngology (BAO). For further information on the latter I can only refer the interested...

Chronic rhinosinusitis management: back to the future?

Immunology is a dim and distant medical school memory to many ENT surgeons, but the increasingly complex immunology of chronic rhinosinusitis is fascinating (honestly!). Medical management options in CRS no longer just involves saline and steroids, and we need to...

The search for pharmacological treatments for hearing loss and tinnitus

Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

The Malawi Hearing Project

Rachael Collins, ENT trainee in the UK, and Mwanaisha Jauza Phiri, audiologist in Malawi, explore the challenges and innovations in delivering ear and hearing care (EHC) across Malawi. The Malawi Hearing Project, a partnership between QECH and Cambridge Global Health...