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2065 results found

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Neuromodulation in drug resistant epilepsy

Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Storytelling is good for your memory

Mild cognitive impairment (MCI) presents a challenging frontier in healthcare due to the limited availability of effective drugs. Despite its prevalence and potential progression to dementia, there remains a notable gap in pharmacological interventions targeting MCI. This month’s Editors’ Choice...

Covid-19 and vestibular symptoms review

Since the coronavirus pandemic, there have been several studies looking into alterations within the auditory system but few in the vestibular system associated with Covid-19. This review delves into the specific evidence. It is challenging to elucidate the link between...

Where ignorance is bliss, 'tis folly to be wise

Our irrepressible Features Editor, Chris Potter, explores the limits of ignorance. I’m not sure about you, but I seem to exist in a sea of incompetence and ignorance, constantly surrounded by amateurish chumps and feckless underachievers. Now, a lesser man...

Endoscopic ‘syringe and cutdown’ technique for nasolacrimal duct obstruction in children

This article presents a novel yet simple technique to help in the management of congenital NLDO. The authors propose it as a valuable addition to existing standard procedures. Congenital nasolacrimal duct obstruction (NLDO) is a condition encountered within the first...

A global online fellowship in head and neck surgery and oncology

The International Federation of Head and Neck Oncologic Societies (IFHNOS) offers an online fellowship training programme for advanced trainees wishing to subspecialise in head and neck surgery and oncology. Emma Stapleton speaks with the Chairman of the Board of Directors...

Staying safe during endoscopic ear surgery

There is growing interest in using rigid endoscopes rather than traditional operative microscopes to perform transcanal middle ear surgery. Rigid endoscopy provides a high resolution, wide-angle view of the tympanic cavity through minimally invasive surgical portals. In this article, Elliott...

Three is not a crowd! Involving family members in audiology appointments

Family members currently have minimal involvement in the appointment. Image by Caitlin Grenness. Hearing loss in older adults not only affects the patients themselves, but also their family members. This article outlines the findings of recent research into how family...

Neural plasticity and aural rehabilitation

Neural plasticity refers to an ability of the brain and central nervous system to change their structure and function or their reorganisation in response to environmental cues, experience, learning, behaviour, injury and / or diseases and treatments. Neural plasticity is...

Rhinology: what does the future hold?

David Kennedy surveys the past, the present and the future of rhinology practice and research. An evolution of understanding in rhinology The dramatic growth of clinical and translational research within the field of rhinology in recent years is illustrated by...