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What is the right balance to strike in the management of anaplastic thyroid cancer?

This is a pragmatic article on a difficult and much debated subject. Management of anaplastic thyroid cancer (ATC) can feel like making decisions between a rock and a hard place, and this article suggests one path to help navigate some...

A study defining septal areas and turbinates that are relevant in assessing patients with nasal obstruction

The symptom of nasal obstruction is subjective when patients present in clinics. The decision to intervene surgically is often made on clinical appearance of the nasal septum and turbinates which, unless extreme, cannot always be judged as different from patients...

Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

OBITUARY: Randall Payne Morton (1948 - 2025)

Randall Payne Morton. Sadly I report the recent death of Randall Payne Morton, Professor of ORL-HNS in Auckland, New Zealand, on the 11 September 2025, after a long and protracted illness. I first met and worked with Randall during his...

Vitamin C, a possible remedy for seasickness?

The internet is full of devices and medicines vying for superiority over which one is the best for preventing seasickness. This study was based on the following observations: elevated histamine levels trigger seasickness; blockade on histidine decarboxylase prevents seasickness while...

Chronic phase of concussion and stability of gaze

It has been known that vestibular symptoms can persist for several months after concussion. The authors designed this study to assess the effect of chronic concussion (more than one year) on gaze stability and the relationship between deficits in gaze...

Persistent imbalance after traumatic brain injury is central in origin

Several residual symptoms, including dizziness and imbalance, can follow traumatic brain injury, no matter how mild. This study focused on the mechanisms, peripheral and central, underlying the complaint of persistent imbalance in patients with chronic mild traumatic brain injury (mTBI)....

Neuro-Ophthalmology and Neuro-Otology: A Case-Based Guide for Clinicians and Scientists

As Daniel Gold points out in his preface, the idea for this title was borne from the observation that, despite the considerable overlap between the fields of neuro-ophthalmology and vestibular neurology, there is no single text that marries these two...

Chronic rhinosinusitis update

There is still a lack of awareness of chronic rhinosinusitis (CRS) despite its burden, calling for events such as the recent Global Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Awareness Day. Research findings from recent publications by Backaert et al have...

Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease

Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...

Associated findings in MRI used for detecting acoustic neuroma

Presently, gadolinium enhanced magnetic resonance imaging is the ‘gold standard’ for investigating acoustic neuroma. There are often ‘incidental’ findings that may or may not be significant. In this study of 109 scans, the authors noted an uptake of 0.9% for...

Prostaglandin versus leukotriene receptor-antagonists in treatment of seasonal allergic rhinitis RCT phase II

Seasonal allergic rhinitis is very common. Failure to control the disease with mono-therapy leads to dual therapy treatment with less compliance and reduced quality of life. A prostaglandin receptor antagonist (ONO-4053) showed some efficacy in controlling allergic rhinitis in animal...