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Bevacizumab, NF2, hearing and age

Introduction NF2-related schwannomatosis (NF2-SWN) is an autosomal dominant disorder leading to the development of schwannomas, meningiomas and spinal cord ependymomas. Younger age is a negative prognostic factor. Treatment includes observation, surgery, radiotherapy and medical therapy with bevacizumab (VEGF monoclonal antibody)....

To question or not to question

Misophonia is a complex condition in which individuals experience a strong negative emotional response to specific sounds, such as chewing, breathing, swallowing or foot tapping. These reactions are not primarily determined by the volume of the sound. Although relatively few...

Hyperacusis and autism spectrum disorder

Several different auditory deficits have been found to be co-morbidities of ASD. This article reviews literature with respect to the relationship between hyperacusis and ASD. Autism spectrum disorder (ASD) can be characterised as a neurodevelopmental condition that is marked by...

Charles Skinner Hallpike and the Hallpike Prize

The British Association of Audiovestibular Physicians introduced the Hallpike Prize in 2009 as an award to stimulate the pursuit of knowledge in relation to the field of audiovestibular medicine. Julian Ahmed celebrates the history of the great man the award...

The effects of hormonal changes across menstrual cycle on high frequency auditory thresholds

Physiological changes during the menstrual cycle are well documented; do these changes extend to the auditory system? Lalsa Shilpa Perepa and Rewa Indurkar delve into the literature to find the evidence. Menstrual cycle refers to a series of changes that...

Why hearing above 8 kHz matters more than you think

This review explores the significance of extended high-frequency hearing loss (above 8 kHz) and why it may be worth doing clinically more frequently. There are many conditions that may hide underneath a normal audiogram, and one of the easiest to...

Could social isolation be a factor in the link between hearing loss and dementia?

In 1802, Beethoven wrote to his brothers Carl and Johann about his hearing loss: “You men who think or say that I am malevolent, stubborn, or misanthropic, how greatly do you wrong me. You do not know the secret cause...

Clinical leadership and management: developing world ENT

I have been asked to share some of the initiatives I have been involved with to address ENT-related challenges in Africa and the developing world. Developing countries constitute the majority of the world’s landmass (Figure 1), are home to >50%...

Diabetes and hearing loss: a review

As hearing health professionals we often ask, especially in older patients, if they have diabetes; but what is the link? How is it manifested and should it change current practice? Alec Lapira reviews the changing evidence. Early attempts to establish...

Recurrent respiratory papilloma treatment in the office

In this interesting new article, Markus Hess and Susanne Fleischer describe their technique for managing recurrent laryngeal papillomatosis in an outpatient setting using channelled endoscopes. The recurrent respiratory papillomatosis (RRP) of the larynx is a chronic HPV-associated viral disease. Clinical...

Partial reconstruction of the pinna

Reconstruction of the pinna is one of the most challenging procedures in facial plastic surgery. Although there has been significant progress since one of the earliest recorded descriptions by Sushruta in 600 BC, the complex three-dimensional structure of the pinna...

Giacomo Puccini’s laryngeal cancer

Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...